[HTML][HTML] Coronavirus biology and replication: implications for SARS-CoV-2

P V'kovski, A Kratzel, S Steiner, H Stalder… - Nature Reviews …, 2021 - nature.com
The SARS-CoV-2 pandemic and its unprecedented global societal and economic disruptive
impact has marked the third zoonotic introduction of a highly pathogenic coronavirus into the …

[HTML][HTML] SARS-CoV-2 vaccines in development

F Krammer - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first reported in late
2019 in China and is the causative agent of the coronavirus disease 2019 (COVID-19) …

REGN-COV2 antibodies prevent and treat SARS-CoV-2 infection in rhesus macaques and hamsters

A Baum, D Ajithdoss, R Copin, A Zhou, K Lanza… - Science, 2020 - science.org
An urgent global quest for effective therapies to prevent and treat coronavirus disease 2019
(COVID-19) is ongoing. We previously described REGN-COV2, a cocktail of two potent …

[HTML][HTML] Development of an inactivated vaccine candidate, BBIBP-CorV, with potent protection against SARS-CoV-2

H Wang, Y Zhang, B Huang, W Deng, Y Quan, W Wang… - Cell, 2020 - cell.com
Summary The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) threatens global public health. The …

[HTML][HTML] Viral and host factors related to the clinical outcome of COVID-19

X Zhang, Y Tan, Y Ling, G Lu, F Liu, Z Yi, X Jia, M Wu… - Nature, 2020 - nature.com
Abstract In December 2019, coronavirus disease 2019 (COVID-19), which is caused by the
new coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was …

[HTML][HTML] SARS-CoV-2 infection in farmed minks, the Netherlands, April and May 2020

N Oreshkova, RJ Molenaar, S Vreman… - …, 2020 - eurosurveillance.org
Respiratory disease and increased mortality occurred in minks on two farms in the
Netherlands, with interstitial pneumonia and SARS-CoV-2 RNA in organ and swab samples …

Broad host range of SARS-CoV-2 predicted by comparative and structural analysis of ACE2 in vertebrates

J Damas, GM Hughes, KC Keough… - Proceedings of the …, 2020 - National Acad Sciences
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is
the cause of COVID-19. The main receptor of SARS-CoV-2, angiotensin I converting enzyme …

The total number and mass of SARS-CoV-2 virions

R Sender, YM Bar-On, S Gleizer… - Proceedings of the …, 2021 - National Acad Sciences
Quantitatively describing the time course of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection within an infected individual is important for …

[HTML][HTML] AXL is a candidate receptor for SARS-CoV-2 that promotes infection of pulmonary and bronchial epithelial cells

S Wang, Z Qiu, Y Hou, X Deng, W Xu, T Zheng, P Wu… - Cell research, 2021 - nature.com
The current coronavirus disease 2019 (COVID-19) pandemic presents a global public health
challenge. The viral pathogen responsible, severe acute respiratory syndrome coronavirus 2 …

[HTML][HTML] Integrated cytokine and metabolite analysis reveals immunometabolic reprogramming in COVID-19 patients with therapeutic implications

N Xiao, M Nie, H Pang, B Wang, J Hu, X Meng… - Nature …, 2021 - nature.com
Cytokine release syndrome (CRS) is a major cause of the multi-organ injury and fatal
outcome induced by SARS-CoV-2 infection in severe COVID-19 patients. Metabolism can …