[HTML][HTML] Comparison of nonhuman primates identified the suitable model for COVID-19

S Lu, Y Zhao, W Yu, Y Yang, J Gao, J Wang… - Signal transduction and …, 2020 - nature.com
Identification of a suitable nonhuman primate (NHP) model of COVID-19 remains
challenging. Here, we characterized severe acute respiratory syndrome coronavirus 2 …

[HTML][HTML] Structurally resolved SARS-CoV-2 antibody shows high efficacy in severely infected hamsters and provides a potent cocktail pairing strategy

S Du, Y Cao, Q Zhu, P Yu, F Qi, G Wang, X Du, L Bao… - Cell, 2020 - cell.com
Understanding how potent neutralizing antibodies (NAbs) inhibit SARS-CoV-2 is critical for
effective therapeutic development. We previously described BD-368-2, a SARS-CoV-2 NAb …

Does SARS‐Cov‐2 invade the brain? Translational lessons from animal models

S Natoli, V Oliveira, P Calabresi… - European journal of …, 2020 - Wiley Online Library
The current coronavirus disease (COVID‐19) outbreak, caused by the novel severe acute
respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has raised the possibility of potential …

[HTML][HTML] Evidence for SARS-CoV-2 infection of animal hosts

AS Abdel-Moneim, EM Abdelwhab - Pathogens, 2020 - mdpi.com
COVID-19 is the first known pandemic caused by a coronavirus, SARS-CoV-2, which is the
third virus in the family Coronaviridae to cause fatal infections in humans after SARS-CoV …

[HTML][HTML] Establishment of an African green monkey model for COVID-19 and protection against re-infection

C Woolsey, V Borisevich, AN Prasad, KN Agans… - Nature …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for an
unprecedented global pandemic of COVID-19. Animal models are urgently needed to study …

Animals and SARS‐CoV‐2: Species susceptibility and viral transmission in experimental and natural conditions, and the potential implications for community …

EC Hobbs, TJ Reid - Transboundary and Emerging Diseases, 2021 - Wiley Online Library
The current COVID‐19 global pandemic, caused by severe acute respiratory syndrome
coronavirus 2 (SARS‐CoV‐2) of probable bat origin, has highlighted the ongoing need for a …

[HTML][HTML] A variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein

W Pang, Y Lu, YB Zhao, F Shen, CF Fan, Q Wang… - Cell Research, 2022 - nature.com
The emerging SARS-CoV-2 variants, commonly with many mutations in S1 subunit of spike
(S) protein are weakening the efficacy of the current vaccines and antibody therapeutics …

[HTML][HTML] NVX-CoV2373 vaccine protects cynomolgus macaque upper and lower airways against SARS-CoV-2 challenge

M Guebre-Xabier, N Patel, JH Tian, B Zhou… - Vaccine, 2020 - Elsevier
There is an urgent need for a safe and protective vaccine to control the global spread of
SARS-CoV-2 and prevent COVID-19. Here, we report the immunogenicity and protective …

[HTML][HTML] Virus infection induced pulmonary fibrosis

WJ Huang, XX Tang - Journal of translational medicine, 2021 - Springer
Pulmonary fibrosis is the end stage of a broad range of heterogeneous interstitial lung
diseases and more than 200 factors contribute to it. In recent years, the relationship between …

[HTML][HTML] Animal models for COVID-19: hamsters, mouse, ferret, mink, tree shrew, and non-human primates

S Shou, M Liu, Y Yang, N Kang, Y Song… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus
causing acute respiratory tract infection in humans. The virus has the characteristics of rapid …