[HTML][HTML] Single-nucleus transcriptomic profiling of multiple organs in a rhesus macaque model of SARS-CoV-2 infection

Q Ma, W Ma, TZ Song, Z Wu, Z Liu, Z Hu… - Zoological …, 2022 - ncbi.nlm.nih.gov
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
diverse clinical manifestations and tissue injuries in multiple organs. However, cellular and …

[HTML][HTML] 2020 update on human coronaviruses: One health, one world

X Zhao, Y Ding, J Du, Y Fan - Medicine in novel technology and devices, 2020 - Elsevier
Since human coronavirus (HCoVs) was first described in the 1960s, seven strains of
respiratory human coronaviruses have emerged and caused human infections. After the …

Nanomedicines targeting respiratory injuries for pulmonary disease management

D Liu, M Long, L Gao, Y Chen, F Li… - Advanced Functional …, 2022 - Wiley Online Library
The respiratory system holds crucial importance in the biology of vertebrate animals. Injuries
of the respiratory system caused by viral infections (eg, by COVID‐19, MERS, and SARS) …

SARS-CoV-2 rapidly adapts in aged BALB/c mice and induces typical pneumonia

Y Zhang, K Huang, T Wang, F Deng, W Gong… - Journal of …, 2021 - Am Soc Microbiol
Age is a risk factor for coronavirus disease 2019 (COVID-19)-associated morbidity and
mortality in humans; hence, in this study, we compared the course of severe acute …

Ligand-based approach for predicting drug targets and for virtual screening against COVID-19

Y Yang, Z Zhu, X Wang, X Zhang, K Mu… - Briefings in …, 2021 - academic.oup.com
Discovering efficient drugs and identifying target proteins are still an unmet but urgent need
for curing coronavirus disease 2019 (COVID-19). Protein structure-based docking is a …

Bioinformatics approaches for unveiling virus-host interactions

H Iuchi, J Kawasaki, K Kubo, T Fukunaga… - Computational and …, 2023 - Elsevier
Abstract The coronavirus disease-2019 (COVID-19) pandemic has elucidated major
limitations in the capacity of medical and research institutions to appropriately manage …

Interspecies transmission of SARS CoV-2 with special emphasis on viral mutations and ACE-2 receptor homology roles

ME Hamdy, AH El Deeb, NM Hagag… - … journal of veterinary …, 2023 - Taylor & Francis
ABSTRACT COVID-19 outbreak was first reported in 2019, Wuhan, China. The spillover of
the disease caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) …

A synthetic peptide CTL vaccine targeting nucleocapsid confers protection from SARS-CoV-2 challenge in rhesus macaques

PE Harris, T Brasel, C Massey, CV Herst, S Burkholz… - Vaccines, 2021 - mdpi.com
Background: Persistent transmission of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has given rise to a COVID-19 pandemic. Several vaccines, conceived in …

Defining the determinants of protection against SARS-CoV-2 infection and viral control in a dose-down Ad26. CoV2. S vaccine study in nonhuman primates

DY Zhu, MJ Gorman, D Yuan, J Yu, NB Mercado… - PLoS …, 2022 - journals.plos.org
Despite the rapid creation of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) vaccines, the precise correlates of immunity against severe Coronavirus Disease …

COVID-19 research: lessons from non-human primate models

L Albrecht, E Bishop, B Jay, B Lafoux, M Minoves… - Vaccines, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
coronavirus disease 2019 (COVID-19). It emerged from China in December 2019 and …