Wheat is a major cereal crop providing energy and nutrients to the billions of people around the world. Gluten is a structural protein in wheat, that is necessary for its dough making …
Over the past decade, the Rosetta biomolecular modeling suite has informed diverse biological questions and engineering challenges ranging from interpretation of low …
Coeliac disease is a common enteropathy that occurs in genetically susceptible individuals in response to the ingestion of gluten proteins present in wheat, rye and barley. Currently …
M Ali, HM Ishqi, Q Husain - Biotechnology and bioengineering, 2020 - Wiley Online Library
Enzyme engineering is a powerful tool to fine‐tune the enzymes. It is a technique by which the stability, activity, and specificity of the enzymes can be altered. The characteristic …
MM Leonard, JA Silvester, D Leffler, A Fasano… - Gastroenterology, 2021 - Elsevier
Background & Aims Gluten challenge is used to diagnose celiac disease (CeD) and for clinical research. Sustained gluten exposure reliably induces histologic changes but is …
G Wei, EJ Helmerhorst, G Darwish, G Blumenkranz… - Nutrients, 2020 - mdpi.com
Celiac disease (CeD) affects about 1% of most world populations. It presents a wide spectrum of clinical manifestations, ranging from minor symptoms to mild or severe …
MV Machado - International journal of molecular sciences, 2023 - mdpi.com
Celiac disease (CD) is a common autoimmune disease affecting around 1% of the population. It consists of an immune-mediated enteropathy, triggered by gluten exposure in …
Gluten is known to be the main triggering factor for celiac disease (CeD), an immune- mediated disorder. CeD is therefore managed using a strict and lifelong gluten-free diet …
HA Besser, C Khosla - Trends in Pharmacological Sciences, 2023 - cell.com
Celiac disease (CeD) is a widespread, gluten-induced, autoimmune disorder that lacks any medicinal therapy. Towards the goal of developing non-dietary treatments for CeD, research …