Polymorphic variants of adrenoceptors: pharmacology, physiology, and role in disease

A Ahles, S Engelhardt - Pharmacological reviews, 2014 - ASPET
The human genome encodes nine different adrenoceptor genes. These are grouped into
three families, namely, the α 1-, α 2-, and β-adrenoceptors, with three family members each …

[HTML][HTML] Large-scale direct targeting for drug repositioning and discovery

C Zheng, Z Guo, C Huang, Z Wu, Y Li, X Chen, Y Fu… - Scientific reports, 2015 - nature.com
A system-level identification of drug-target direct interactions is vital to drug repositioning
and discovery. However, the biological means on a large scale remains challenging and …

The effects of intraoperative esmolol infusion on the postoperative pain and hemodynamic stability after rhinoplasty

S Vahabi, Y Rafieian… - Journal of Investigative …, 2018 - Taylor & Francis
Background: Esmolol an ultrashort acting cardioselective β1-adrenergic receptor
antagonist), has been successfully employed for perioperative sympatholysis. In this study …

Benefits and safety of landiolol for rapid rate control in patients with atrial tachyarrhythmias and acute decompensated heart failure

T Shiga - European Heart Journal Supplements, 2022 - academic.oup.com
Atrial tachyarrhythmias often occur in patients with worsening heart failure (HF), and the
development of atrial tachyarrhythmias in acute decompensated HF (ADHF) causes an …

Voltammetric hybridization assay for the β1-adrenergic receptor gene (ADRB1), a marker for hypertension, by using a metal organic framework (Fe-MIL-88NH2) with …

G Yuan, L Wang, D Mao, F Wang, J Zhang - Microchimica Acta, 2017 - Springer
The β1 receptor blocker metoprolol targets the hypertension-carrying adrenergic receptor
gene (ADRB1), but therapy is often hindered by a lack of evidence-based medical …

Genetic variation in the β1-adrenergic receptor is associated with the risk of atrial fibrillation after cardiac surgery

JM Jeff, BS Donahue, K Brown-Gentry, DM Roden… - American heart …, 2014 - Elsevier
Background Postoperative atrial fibrillation (PoAF) after cardiac surgery is common and
associated with increased morbidity and mortality. Increased sympathetic activation after …

Heart rate as a predictor and a therapeutic target of cardiac ischemic complications after non-cardiac surgery. A narrative review

BB Pinto, B Walder - Trends in Anaesthesia and Critical Care, 2018 - Elsevier
Postoperative cardiac ischemic complications are frequent and strongly associated with
postoperative mortality. Elevated heart rate before, during and after surgery increases the …

Effects of sex and the common ADRB1 389 genetic polymorphism on the hemodynamic response to dobutamine

D Yogev, M Basheer, S Blotnick, Y Caraco… - Pharmacogenetics …, 2015 - journals.lww.com
Results Resting heart rate (HR) response to 6 mcg/kg/min dobutamine (ΔHR) was 4.7-fold
larger in Arg389Arg than in Gly389Gly [(mean±SD) 12.95±6.99, 2.75±1.65 bpm …

[HTML][HTML] Pharmacokinetic parameters and over-responsiveness of Iranian population to propranolol

E Salehifar, S Ebrahim, MR Shiran… - Advanced …, 2017 - ncbi.nlm.nih.gov
Purpose: Propranolol is the most widely used treatment for cardiovascular diseases. Dosage
range in our patients is usually less than the amount mentioned in references. The aim of the …

β1 肾上腺素能受体基因多态性在心血管病方面的研究进展

李俊萍, 郭晓华 - 包头医学院学报, 2015 - cqvip.com
β1肾上腺素能受体基因多态性在心血管病方面的研究进展-[维普官方网站]-www.cqvip.com-维普
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