Therapeutic potential and mechanisms of mesenchymal stem cell-derived exosomes as bioactive materials in tendon–bone healing

J Zou, W Yang, W Cui, C Li, C Ma, X Ji, J Hong… - Journal of …, 2023 - Springer
Tendon–bone insertion (TBI) injuries, such as anterior cruciate ligament injury and rotator
cuff injury, are the most common soft tissue injuries. In most situations, surgical …

A review of low-intensity pulsed ultrasound for therapeutic applications

X Jiang, O Savchenko, Y Li, S Qi, T Yang… - IEEE Transactions …, 2018 - ieeexplore.ieee.org
Ultrasound therapy has a long history of novel applications in medicine. Compared to high-
intensity ultrasound used for tissue heating, low-intensity ultrasound has drawn increasing …

The effects of LIPUS on soft-tissue healing: a review of literature

A Khanna, RTC Nelmes, N Gougoulias… - British medical …, 2009 - academic.oup.com
Introduction Ultrasound is widely used for imaging purposes and as an adjunct to
physiotherapy. Low-intensity pulsed ultrasound (LIPUS), having removed the thermal …

Role of the neurologic system in fracture healing: an extensive review

RS Parker, MK Nazzal, AJ Morris… - Current Osteoporosis …, 2024 - Springer
Abstract Purpose of Review Despite advances in orthopedics, there remains a need for
therapeutics to hasten fracture healing. However, little focus is given to the role the nervous …

Biology and augmentation of tendon-bone insertion repair

PPY Lui, P Zhang, KM Chan, L Qin - Journal of orthopaedic surgery and …, 2010 - Springer
Surgical reattachment of tendon and bone such as in rotator cuff repair, patellar-patella
tendon repair and anterior cruciate ligament (ACL) reconstruction often fails due to the …

Low-intensity pulsed ultrasound augments tendon, ligament, and bone–soft tissue healing in preclinical animal models: a systematic review

WC Lai, BC Iglesias, BJ Mark, D Wang - Arthroscopy: The Journal of …, 2021 - Elsevier
Purpose To appraise the available animal and human studies investigating low-intensity
pulsed ultrasound stimulation (LIPUS) on tendon, ligament, and bone–soft tissue (B-ST) …

Cytokines in rotator cuff degeneration and repair

A Bedi, T Maak, C Walsh, SA Rodeo, D Grande… - Journal of Shoulder and …, 2012 - Elsevier
The pathogenesis of rotator cuff degeneration remains poorly defined, and the incidence of
degenerative tears is increasing in the aging population. Rates of recurrent tear and …

[HTML][HTML] Exosomes from CD133+ human urine-derived stem cells combined adhesive hydrogel facilitate rotator cuff healing by mediating bone marrow mesenchymal …

X Tong, Y Xu, T Zhang, C Deng, J Xun, D Sun… - Journal of Orthopaedic …, 2023 - Elsevier
Background The inadequate regeneration of natural tissue (mainly fibrocartilage) between
tendon and bone during rotator cuff (RC) repair results in an unsatisfactory quality of RC …

Book-shaped Acellular fibrocartilage scaffold with cell-loading capability and Chondrogenic Inducibility for tissue-engineered fibrocartilage and bone–tendon healing

C Chen, F Liu, Y Tang, J Qu, Y Cao… - … applied materials & …, 2019 - ACS Publications
Functional fibrocartilage regeneration is a bottleneck during bone–tendon healing, and the
currently available tissue-engineering strategies for fibrocartilage regeneration are …

[HTML][HTML] Exosomes secreted by hypoxia-stimulated bone-marrow mesenchymal stem cells promote grafted tendon-bone tunnel healing in rat anterior cruciate ligament …

T Zhang, S Yan, Y Song, C Chen, D Xu, B Lu… - Journal of orthopaedic …, 2022 - Elsevier
Background After anterior cruciate ligament (ACL) reconstruction in clinic, firm and rapid
integration of the grafted tendon into the bone tunnel remains a challenge. Exosomes from …