Antibiotic-resistant ESKAPE pathogens and COVID-19: the pandemic beyond the pandemic

A Catalano, D Iacopetta, J Ceramella, M Pellegrino… - Viruses, 2023 - mdpi.com
Antibacterial resistance is a renewed public health plague in modern times, and the COVID-
19 pandemic has rekindled this problem. Changes in antibiotic prescribing behavior …

Dynamics of the microbiota and its relationship with post-COVID-19 syndrome

NC Moreno-Corona, O López-Ortega… - International Journal of …, 2023 - mdpi.com
Coronavirus disease (COVID-19) is an infection caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), which can be asymptomatic or present with multiple …

Complexes of ruthenium (II) as promising dual-active agents against cancer and viral infections

A D'Amato, A Mariconda, D Iacopetta, J Ceramella… - Pharmaceuticals, 2023 - mdpi.com
Poor responses to medical care and the failure of pharmacological treatment for many high-
frequency diseases, such as cancer and viral infections, have been widely documented. In …

Impact of cytochrome P450 enzymes on the phase I metabolism of drugs

D Iacopetta, J Ceramella, A Catalano, E Scali… - Applied Sciences, 2023 - mdpi.com
The cytochrome P450 (CYP) enzyme family is the major enzyme system catalyzing the
phase I metabolism of xenobiotics, including pharmaceuticals and toxic compounds in the …

Metal Complexes with Schiff Bases as Antimicrobials and Catalysts

D Iacopetta, J Ceramella, A Catalano, A Mariconda… - Inorganics, 2023 - mdpi.com
Complexes of Schiff bases (SBs) with metals are promising compounds exhibiting a broad
range of applications, such as catalysts, polymers, dyes, and several biological activities …

COVID-19 biomarkers at the crossroad between patient stratification and targeted therapy: the role of validated and proposed parameters

M Rizzi, D D'Onghia, S Tonello, R Minisini… - International Journal of …, 2023 - mdpi.com
Clinical knowledge about SARS-CoV-2 infection mechanisms and COVID-19
pathophysiology have enormously increased during the pandemic. Nevertheless, because …

A comprehensive update of various attempts by medicinal chemists to combat COVID-19 through natural products

A Rafiq, T Jabeen, S Aslam, M Ahmad, UA Ashfaq… - Molecules, 2023 - mdpi.com
The ongoing COVID-19 pandemic has resulted in a global panic because of its continual
evolution and recurring spikes. This serious malignancy is caused by the severe acute …

COVID-19 inflammatory markers and vitamin D relationship in pediatric patients

IC Bagiu, IL Scurtu, DI Horhat, IC Mot, RM Horhat… - Life, 2022 - mdpi.com
Background: Biomarkers play an important role in COVID-19, and more research in this
regard is needed, especially in the case of children. This study aimed to look for a link …

Antiviral effect of ephedrine alkaloids-free ephedra herb extract against SARS-CoV-2 in vitro

M Uema, M Hyuga, K Yonemitsu, S Hyuga, Y Amakura… - Microorganisms, 2023 - mdpi.com
We report for the first time that ephedrine alkaloids-free Ephedra Herb extract (EFE) directly
inhibits the replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in …

A clinical update on SARS-CoV-2: Pathology and development of potential inhibitors

DD Singh, I Han, EH Choi, DK Yadav - Current Issues in Molecular …, 2023 - mdpi.com
SARS-CoV-2 (severe acute respiratory syndrome) is highly infectious and causes severe
acute respiratory distress syndrome (SARD), immune suppression, and multi-organ failure …