[HTML][HTML] Potential therapeutic use of the rosemary diterpene carnosic acid for Alzheimer's disease, Parkinson's disease, and long-COVID through NRF2 activation to …
Rosemary (Rosmarinus officinalis [family Lamiaceae]), an herb of economic and gustatory
repute, is employed in traditional medicines in many countries. Rosemary contains carnosic …
repute, is employed in traditional medicines in many countries. Rosemary contains carnosic …
Targeting cellular senescence in cancer by plant secondary metabolites: A systematic review
Senescence suppresses tumor growth, while also developing a tumorigenic state in the
nearby cells that is mediated by senescence-associated secretory phenotypes (SASPs). The …
nearby cells that is mediated by senescence-associated secretory phenotypes (SASPs). The …
In silico evaluation of food‐derived carotenoids against SARS‐CoV‐2 drug targets: Crocin is a promising dietary supplement candidate for COVID‐19
The current COVID‐19 pandemic is severely threatening public healthcare systems around
the globe. Some supporting therapies such as remdesivir, favipiravir, and ivermectin are still …
the globe. Some supporting therapies such as remdesivir, favipiravir, and ivermectin are still …
In silico discovery of multi-targeting inhibitors for the COVID-19 treatment by molecular docking, molecular dynamics simulation studies, and ADMET predictions
Abstract Coronavirus disease-2019 (COVID-19), a global pandemic, has currently infected
more than 247 million people around the world. Nowadays, several receptors of COVID-19 …
more than 247 million people around the world. Nowadays, several receptors of COVID-19 …
[HTML][HTML] Immune signature of covid-19: In-depth reasons and consequences of the cytokine storm
P Niedźwiedzka-Rystwej, A Majchrzak… - International Journal of …, 2022 - mdpi.com
In the beginning of the third year of the fight against COVID-19, the virus remains at least still
one step ahead in the pandemic “war”. The key reasons are evolving lineages and …
one step ahead in the pandemic “war”. The key reasons are evolving lineages and …
[HTML][HTML] Modulation of TLR/NF-κB/NLRP signaling by bioactive phytocompounds: A promising strategy to augment cancer chemotherapy and immunotherapy
Background Tumors often progress to a more aggressive phenotype to resist drugs. Multiple
dysregulated pathways are behind this tumor behavior which is known as cancer …
dysregulated pathways are behind this tumor behavior which is known as cancer …
[HTML][HTML] NSAIDs and Kelleni's protocol as potential early COVID-19 treatment game changer: could it be the final countdown?
MT Kelleni - Inflammopharmacology, 2022 - Springer
We have previously published several papers illustrating numerous immunomodulatory and
anti-inflammatory potential benefits when we repurposed safe, generic non-steroidal anti …
anti-inflammatory potential benefits when we repurposed safe, generic non-steroidal anti …
Current advances in nanoformulations of therapeutic agents targeting tumor microenvironment to overcome drug resistance
The tumor microenvironment (TME) plays a pivotal role in cancer development and
progression. In this line, revealing the precise mechanisms of the TME and associated …
progression. In this line, revealing the precise mechanisms of the TME and associated …
[HTML][HTML] Marine compounds, mitochondria, and malignancy: a therapeutic nexus
The marine environment is important yet generally underexplored. It contains new sources
of functional constituents that can affect various pathways in food processing, storage, and …
of functional constituents that can affect various pathways in food processing, storage, and …
[HTML][HTML] Quercetin derivatives in combating spinal cord injury: a mechanistic and systematic review
Spinal cord injury (SCI) possesses a complicated etiology. There is no FDA-approved
treatment for SCI, and the majority of current interventions focus on reducing symptoms …
treatment for SCI, and the majority of current interventions focus on reducing symptoms …