Monoclonal antibodies for the management of central nervous system diseases: Clinical success and future strategies
Introduction Recombinant monoclonal antibodies (mAbs) are highly selective and effective
biologicals with proven utility as therapeutics. mAbs have demonstrated substantial promise …
biologicals with proven utility as therapeutics. mAbs have demonstrated substantial promise …
Interleukin-21 Influences Glioblastoma Course: Biological Mechanisms and Therapeutic Potential
A Repici, A Ardizzone, A Filippone, C Colarossi… - Cells, 2023 - mdpi.com
Brain tumors represent a heterogeneous group of neoplasms involving the brain or nearby
tissues, affecting populations of all ages with a high incidence worldwide. Among the …
tissues, affecting populations of all ages with a high incidence worldwide. Among the …
Signaling Pathways of AXL Receptor Tyrosine Kinase Contribute to the Pathogenetic Mechanisms of Glioblastoma
A Repici, A Ardizzone, F De Luca, L Colarossi… - Cells, 2024 - mdpi.com
Brain tumors are a diverse collection of neoplasms affecting the brain with a high prevalence
rate in people of all ages around the globe. In this pathological context, glioblastoma, a form …
rate in people of all ages around the globe. In this pathological context, glioblastoma, a form …
Pentraxin 3: A Main Driver of Inflammation and Immune System Dysfunction in the Tumor Microenvironment of Glioblastoma
SA Scuderi, A Ardizzone, AE Salako, G Pantò… - Cancers, 2024 - mdpi.com
Simple Summary Brain tumors, including glioblastoma (GB), pose a significant health
concern globally, with high mortality rates despite current therapies. Pentraxin 3 (PTX3) is a …
concern globally, with high mortality rates despite current therapies. Pentraxin 3 (PTX3) is a …