LncRNAs in cancer: regulatory and therapeutic implications

A Nandwani, S Rathore, M Datta - Cancer letters, 2021 - Elsevier
Long noncoding RNAs (lncRNAs) comprise a class of RNAs that do not code for proteins but
are critical in regulating diverse cellular processes and maintaining cell function. In doing so …

Exosomal-long non-coding RNAs journey in colorectal cancer: Evil and goodness faces of key players

NI Rizk, AI Abulsoud, MM Kamal, DH Kassem… - Life sciences, 2022 - Elsevier
Exosomes are nano-vesicles (NVs) secreted by cells and take part in cell-cell
communications. Lately, these exosomes were proved to have dual faces in cancer …

The emerging roles and potential applications of circular RNAs in ovarian cancer: a comprehensive review

S Najafi - Journal of Cancer Research and Clinical Oncology, 2023 - Springer
Ovarian cancer (OC) is among the most common human malignancies and the first cause of
deaths among gynecologic cancers. Early diagnosis can help improving prognosis in those …

Dual relationship between long non-coding RNAs and STAT3 signaling in different cancers: New insight to proliferation and metastasis

M Ashrafizadeh, MH Gholami, S Mirzaei, A Zabolian… - Life sciences, 2021 - Elsevier
Uncontrolled growth and metastasis of cancer cells is an increasing challenge for
overcoming cancer, and improving survival of patients. Complicated signaling networks …

Role of different non-coding RNAs as ovarian cancer biomarkers

A Beg, R Parveen, H Fouad, ME Yahia… - Journal of Ovarian …, 2022 - Springer
Background Among many gynecological malignancies ovarian cancer is the most prominent
and leading cause of female mortality worldwide. Despite extensive research, the underlying …

Aptamers as potential therapeutic tools for ovarian cancer: Advancements and challenges

W Szymanowski, A Szymanowska, A Bielawska… - Cancers, 2023 - mdpi.com
Simple Summary Aptamers are versatile molecules for cancer treatment. They can be used
to target specific molecules, conjugated to additional nucleic acid moieties or payloads. In …

Non-Coding RNAs: Foes or Friends for Targeting Tumor Microenvironment

A Szymanowska, C Rodriguez-Aguayo… - Non-coding RNA, 2023 - mdpi.com
Non-coding RNAs (ncRNAs) are a group of molecules critical for cell development and
growth regulation. They are key regulators of important cellular pathways in the tumor …

Role of a pyroptosis-related lncRNA signature in risk stratification and immunotherapy of ovarian cancer

Z Zhang, Z Xu, Y Yan - Frontiers in Medicine, 2022 - frontiersin.org
Background: Pyroptosis is a newly recognized form of cell death. Emerging evidence has
suggested the crucial role of long non-coding RNAs (lncRNAs) in the tumorigenesis and …

PVT1 is a stress-responsive lncRNA that drives ovarian cancer metastasis and chemoresistance

K Tabury, M Monavarian, E Listik… - Life Science …, 2022 - life-science-alliance.org
Metastatic growth of ovarian cancer cells into the peritoneal cavity requires adaptation to
various cellular stress factors to facilitate cell survival and growth. Here, we demonstrate the …

Coding roles of long non-coding RNAs in breast cancer: Emerging molecular diagnostic biomarkers and potential therapeutic targets with special reference to …

D Kashyap, R Sharma, N Goel, HS Buttar… - Frontiers in …, 2023 - frontiersin.org
Dysregulation of epigenetic mechanisms have been depicted in several pathological
consequence such as cancer. Different modes of epigenetic regulation (DNA methylation …