CCR5 is among the most studied chemokine receptors due to its profound significance in
human health and disease. The notion that CCR5 is a functionally redundant receptor was …

COVID-19 pandemic represented a worldwide major challenge in different areas, and efforts
undertaken by the scientific community led to the understanding of some of the genetic …

Non-small cell lung cancer (NSCLC) accounts for the vast majority of cases of lung
neoplasms. It is formed in multiple stages, with interactions between environmental risk …

Abstract Human Immunodeficiency Virus (HIV) infection dynamics is strongly influenced by
the host genetic background. NKG2C is an activating receptor expressed mainly on Natural …

The CC chemokine receptor type 5 (CCR5) expressed on immune cells supports
inflammatory responses by directing cells to the inflammation site. CCR5 is also a major …

Abstract The Human Leukocyte Antigen G (HLA-G) is an immunoregulatory molecule with a
critical role in pregnancy success. HLA-G alleles are associated with differential …

This study investigated the impacts of CCR5 promoter region polymorphisms on the
development of systemic lupus erythematosus (SLE) by comparing CCR5 genotypes and …

The chemokine receptor variant CCR5delta32 is linked to HIV-1 infection resistance and
other pathological conditions. In European populations, the allele frequency ranges from 10 …

Non-small cell lung cancer (NSCLC) accounts for the vast majority of cases of lung
neoplasms. It is formed in multiple stages, with interactions between environmental risk …

Introdução: Lúpus Eritematoso Sistêmico (LES) é uma doença autoimune inflamatória
crônica e complexa caracterizada por atividade anormal das células B e T [1, 2], produção …