Abstract Background and Hypothesis Schizophrenia manifests with marked heterogeneity in
both clinical presentation and underlying biology. Modeling individual differences within …

The capability to monitor the mechanical forces on the intervertebral disc (IVD) after
discectomy could develop personalized rehabilitation strategies to benefit the patients´ …

As a highly heterogeneous disorder, schizophrenia shows notable interindividual variation
in clinical manifestations. On that account, an increasing number of studies begin to …

Background The neural underpinnings of bipolar disorder (BD) remain poorly understood.
The cerebellum is ideally positioned to modulate emotional regulation circuitry yet has been …

Schizophrenia lacks a clear definition at the neuroanatomical level, capturing the sites of
origin and progress of this disorder. Using a network-theory approach called epicenter …

Considerable variations exist in the clinical presentation of psychiatric disorders. For any
given diagnostic construct, there are several thousand combinations of symptoms that can …

Background Early psychosis in first-episode psychosis (FEP) and clinical high-risk (CHR)
individuals has been associated with alterations in mean regional measures of brain …

Abnormal default mode network (DMN) connectivity has been found in schizophrenia and
other psychotic disorders. However, there are limited studies on early onset psychosis …

Brainstem regions support vital bodily functions, yet their genetic architectures and
involvement in common brain disorders remain understudied. Here, using imaging-genetics …

Abstract Machine learning can be used to define subtypes of psychiatric conditions based
on shared biological foundations of mental disorders. Here we analyzed cross-sectional …