The humoral response and antibodies against SARS-CoV-2 infection

H Qi, B Liu, X Wang, L Zhang - Nature Immunology, 2022 - nature.com
Two and a half years into the COVID-19 pandemic, we have gained many insights into the
human antibody response to the causative SARS-CoV-2 virus. In this Review, we …

Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

[HTML][HTML] Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response

CY Lin, J Wolf, DC Brice, Y Sun, M Locke, S Cherry… - Cell Host & Microbe, 2022 - cell.com
SARS-CoV-2 infection causes diverse outcomes ranging from asymptomatic infection to
respiratory distress and death. A major unresolved question is whether prior immunity to …

Antibody and B cell responses to SARS-CoV-2 infection and vaccination: the end of the beginning

K Röltgen, SD Boyd - Annual Review of Pathology: Mechanisms …, 2024 - annualreviews.org
As the COVID-19 pandemic has evolved during the past years, interactions between human
immune systems, rapidly mutating and selected SARS-CoV-2 viral variants, and effective …

[HTML][HTML] Determinants of early antibody responses to COVID-19 mRNA vaccines in a cohort of exposed and naïve healthcare workers

G Moncunill, R Aguilar, M Ribes, N Ortega, R Rubio… - …, 2022 - thelancet.com
Background Two doses of mRNA vaccination have shown> 94% efficacy at preventing
COVID-19 mostly in naïve adults, but it is not clear if the second dose is needed to maximize …

COVID-19 vaccine booster dose needed to achieve Omicron-specific neutralisation in nursing home residents

DH Canaday, OA Oyebanji, E White, D Keresztesy… - …, 2022 - thelancet.com
Background Nursing home (NH) residents have borne a disproportionate share of SARS-
CoV-2 morbidity and mortality. Vaccines have limited hospitalisation and death from earlier …

[HTML][HTML] Role of the humoral immune response during COVID-19: guilty or not guilty?

M Yaugel-Novoa, T Bourlet, S Paul - Mucosal Immunology, 2022 - Elsevier
Systemic and mucosal humoral immune responses are crucial to fight respiratory viral
infections in the current pandemic of COVID-19 caused by the SARS-CoV-2 virus. During …

Boosting of cross-reactive antibodies to endemic coronaviruses by SARS-CoV-2 infection but not vaccination with stabilized spike

AR Crowley, H Natarajan, AP Hederman, CA Bobak… - Elife, 2022 - elifesciences.org
Preexisting antibodies to endemic coronaviruses (CoV) that cross-react with SARS-CoV-2
have the potential to influence the antibody response to COVID-19 vaccination and infection …

Evidence for increased SARS-CoV-2 susceptibility and COVID-19 severity related to pre-existing immunity to seasonal coronaviruses

PR Wratil, NA Schmacke, B Karakoc, A Dulovic… - Cell reports, 2021 - cell.com
The importance of pre-existing immune responses to seasonal endemic coronaviruses
(HCoVs) for the susceptibility to SARS-CoV-2 infection and the course of COVID-19 is the …

SARS-CoV-2 infection, vaccination, and antibody response trajectories in adults: a cohort study in Catalonia

M Karachaliou, G Moncunill, A Espinosa… - BMC medicine, 2022 - Springer
Background Heterogeneity of the population in relation to infection, COVID-19 vaccination,
and host characteristics is likely reflected in the underlying SARS-CoV-2 antibody …