The clinical course and outcome of COVID-19 are highly variable, ranging from asymptomatic infections to severe disease and death. Understanding the risk factors of …
SARS-CoV-2 infection causes diverse outcomes ranging from asymptomatic infection to respiratory distress and death. A major unresolved question is whether prior immunity to …
K Röltgen, SD Boyd - Annual Review of Pathology: Mechanisms …, 2024 - annualreviews.org
As the COVID-19 pandemic has evolved during the past years, interactions between human immune systems, rapidly mutating and selected SARS-CoV-2 viral variants, and effective …
Background Two doses of mRNA vaccination have shown> 94% efficacy at preventing COVID-19 mostly in naïve adults, but it is not clear if the second dose is needed to maximize …
Background Nursing home (NH) residents have borne a disproportionate share of SARS- CoV-2 morbidity and mortality. Vaccines have limited hospitalisation and death from earlier …
M Yaugel-Novoa, T Bourlet, S Paul - Mucosal Immunology, 2022 - Elsevier
Systemic and mucosal humoral immune responses are crucial to fight respiratory viral infections in the current pandemic of COVID-19 caused by the SARS-CoV-2 virus. During …
AR Crowley, H Natarajan, AP Hederman, CA Bobak… - Elife, 2022 - elifesciences.org
Preexisting antibodies to endemic coronaviruses (CoV) that cross-react with SARS-CoV-2 have the potential to influence the antibody response to COVID-19 vaccination and infection …
PR Wratil, NA Schmacke, B Karakoc, A Dulovic… - Cell reports, 2021 - cell.com
The importance of pre-existing immune responses to seasonal endemic coronaviruses (HCoVs) for the susceptibility to SARS-CoV-2 infection and the course of COVID-19 is the …
Background Heterogeneity of the population in relation to infection, COVID-19 vaccination, and host characteristics is likely reflected in the underlying SARS-CoV-2 antibody …