[HTML][HTML] Clinical criteria for COVID-19-associated hyperinflammatory syndrome: a cohort study
Background A subset of patients with COVID-19 develops a hyperinflammatory syndrome
that has similarities with other hyperinflammatory disorders. However, clinical criteria …
that has similarities with other hyperinflammatory disorders. However, clinical criteria …
[HTML][HTML] Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial
PL Tharaux, G Pialoux, A Pavot, X Mariette… - The Lancet …, 2021 - thelancet.com
Background Patients with COVID-19 pneumonia have an excess of inflammation and
increased concentrations of cytokines including interleukin-1 (IL-1). We aimed to determine …
increased concentrations of cytokines including interleukin-1 (IL-1). We aimed to determine …
Effect of canakinumab vs placebo on survival without invasive mechanical ventilation in patients hospitalized with severe COVID-19: a randomized clinical trial
Importance Effective treatments for patients with severe COVID-19 are needed. Objective To
evaluate the efficacy of canakinumab, an anti–interleukin-1β antibody, in patients …
evaluate the efficacy of canakinumab, an anti–interleukin-1β antibody, in patients …
Covid-19 and autoimmunity
Though the exact etiology of autoimmune diseases still remains unknown, there are various
factors which are believed to contribute to the emergence of an autoimmune disease in a …
factors which are believed to contribute to the emergence of an autoimmune disease in a …
The immune system and COVID-19: Friend or foe?
F Yazdanpanah, MR Hamblin, N Rezaei - Life sciences, 2020 - Elsevier
Abstract Aim Coronavirus disease 2019 (COVID-19) is a novel highly contagious infection
caused by SARS-CoV-2, which has been became a global public health challenge. The …
caused by SARS-CoV-2, which has been became a global public health challenge. The …
[HTML][HTML] A comprehensive review of viral characteristics, transmission, pathophysiology, immune response, and management of SARS-CoV-2 and COVID-19 as a …
COVID-19 emerged from China in December 2019 and during 2020 spread to every
continent including Antarctica. The coronavirus, SARS-CoV-2, has been identified as the …
continent including Antarctica. The coronavirus, SARS-CoV-2, has been identified as the …
Deciphering the COVID‐19 cytokine storm: systematic review and meta‐analysis
R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
Introduction The coronavirus pandemic has affected more than 20 million people so far.
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …
Preliminary predictive criteria for COVID-19 cytokine storm
R Caricchio, M Gallucci, C Dass, X Zhang… - Annals of the …, 2021 - ard.bmj.com
Objectives To develop predictive criteria for COVID-19-associated cytokine storm (CS), a
severe hyperimmune response that results in organ damage in some patients infected with …
severe hyperimmune response that results in organ damage in some patients infected with …
[HTML][HTML] Temporal and spatial heterogeneity of host response to SARS-CoV-2 pulmonary infection
The relationship of SARS-CoV-2 pulmonary infection and severity of disease is not fully
understood. Here we show analysis of autopsy specimens from 24 patients who succumbed …
understood. Here we show analysis of autopsy specimens from 24 patients who succumbed …
Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19-associated cytokine storm …
S Ramiro, RLM Mostard, C Magro-Checa… - Annals of the …, 2020 - ard.bmj.com
Objectives To prospectively investigate in patients with severe COVID-19-associated
cytokine storm syndrome (CSS) whether an intensive course of glucocorticoids with or …
cytokine storm syndrome (CSS) whether an intensive course of glucocorticoids with or …