Background Animal models and few clinical reports suggest the involvement of the
complement system in the onset of severe manifestations of coronavirus disease-2019 …

Abstract SARS coronavirus 2 (SARS-CoV-2) is a novel viral pathogen that causes a clinical
disease called coronavirus disease 2019 (COVID-19). Although most COVID-19 cases are …

OBJECTIVES: To describe presentation, hospital course, and predictors of bad outcome in
multisystem inflammatory syndrome in children (MIS-C). METHODS: Retrospective data …

Cytokine storm syndrome (CSS), which is frequently fatal, has garnered increased attention
with the ongoing coronavirus pandemic. A variety of hyperinflammatory conditions …

Interferon-γ (IFNγ) is a pleiotropic cytokine with multiple effects on the inflammatory
response and on innate and adaptive immunity. Overproduction of IFNγ underlies several …

Objective Approximately 5% of patients with coronavirus disease 2019 (COVID-19) develop
a life-threatening pneumonia that often occurs in the setting of increased inflammation or …

The coronavirus disease 2019 (COVID-19) pandemic has infected> 22.7 million and led to
the deaths of 795,000 people worldwide. Patients with diabetes are highly susceptible to …

COVID-19 is not deadly early in life, but mortality increases exponentially with age, which is
the strongest predictor of mortality. Mortality is higher in men than in women, because men …

In the midst of resurging COVID-19 cases, the second NIH/FDA virtual COVID-19 and
Cytokines symposium was held on 1 December 2020, focusing on longitudinal studies of …

Background The highest number of COVID-19 cases in Italy have been reported in
Lombardy, a region in northern Italy. We aimed to analyse the course of severe acute …