Major depressive disorder (MDD), also referred to as depression, is one of the most common
psychiatric disorders with a high economic burden. The etiology of depression is still not …

The orbitofrontal cortex in primates including humans is the key brain area in emotion, and
in the representation of reward value and in non-reward, that is not obtaining an expected …

Neural plasticity, a fundamental mechanism of neuronal adaptation, is disrupted in
depression. The changes in neural plasticity induced by stress and other negative stimuli …

Background Depression is a prevalent mental health challenge. Current depression
assessment methods using self-reported and clinician-administered questionnaires have …

Youth depression has been associated with heterogenous patterns of aberrant brain
connectivity. To make sense of these divergent findings, we conducted a systematic review …

We describe evidence for dissociable roles of the medial and lateral orbitofrontal cortex
(OFC) in major depressive disorder (MDD) from structure, functional activation, functional …

Background Although dysfunction of amygdala-related circuits is centrally implicated in
major depressive disorder (MDD), little is known about how this dysfunction differs between …

The amygdala is central to the pathophysiology of many psychiatric illnesses. An imprecise
understanding of how the amygdala fits into the larger network organization of the human …

The Research Domain Criteria (RDoC) initiative provides a strategy for classifying
psychopathology based on behavioral dimensions and neurobiological measures …

Probiotics are currently the subject of intensive research pursuits and also represent a multi-
billion-dollar global industry given their vast potential to improve human health. In addition …