The endoplasmic reticulum (ER) and mitochondria are interconnected intracellular
organelles with vital roles in the regulation of cell signaling and function. While the ER …

Mitochondria are the sites of oxidative metabolism in eukaryotes where the metabolites of
sugars, fats, and amino acids are oxidized to harvest energy. Notably, mitochondria store …

Background Diabetes is associated with an increased risk of cognitive decline and
dementia. These diseases are linked with mitochondrial dysfunction, most likely as a …

Methods A literature search (up to April 2022) was conducted through PubMed database,
and the search range was limited to publications in English. After further literature search …

Rationale: Intermittent hypoxia (IH) is one of the main features of sleep-disordered breathing
(SDB). Recent findings indicate that hypoxia inducible factor-1 (HIF-1) promotes …

Cardiovascular remodeling occurs in cardiomyocytes, collagen meshes, and vascular beds
in the progress of cardiac insufficiency caused by a variety of cardiac diseases such as …

Coronary artery disease has one of the highest mortality rates in the country, and methods
such as thrombolysis and percutaneous coronary intervention (PCI) can effectively improve …

Hepatic ischemia/reperfusion (I/R) injury contributes to morbidity and mortality during liver
resection or transplantation, with limited effective treatments available. Here, we investigated …

Endoplasmic reticulum (ER) and mitochondrial dysfunction play fundamental roles in the
pathogenesis of diabetic retinopathy (DR). However, the interrelationship between the ER …

The mitochondrial‐associated endoplasmic reticulum membrane (MAM) is located between
the outer mitochondrial membrane and the endoplasmic reticulum membrane. The MAM is …