Caspases and therapeutic potential of caspase inhibitors in moderate–severe SARS‐CoV‐2 infection and long COVID

M Plassmeyer, O Alpan, MJ Corley, TA Premeaux… - Allergy, 2022 - Wiley Online Library
Background COVID‐19 can present with lymphopenia and extraordinary complex
multiorgan pathologies that can trigger long‐term sequela. Aims Given that inflammasome …

Probiotics, photobiomodulation, and disease management: Controversies and challenges

LM Ailioaie, G Litscher - International Journal of Molecular Sciences, 2021 - mdpi.com
In recent decades, researchers around the world have been studying intensively how micro-
organisms that are present inside living organisms could affect the main processes of life …

Cognitive impairment after long COVID-19: Current evidence and perspectives

Z Li, Z Zhang, Z Zhang, Z Wang, H Li - Frontiers in Neurology, 2023 - frontiersin.org
COVID-19, caused by the SARS-CoV-2 virus, is a respiratory infectious disease. While most
patients recover after treatment, there is growing evidence that COVID-19 may result in …

[HTML][HTML] Prevention and treatment of COVID-19: Focus on interferons, chloroquine/hydroxychloroquine, azithromycin, and vaccine

BM Bakadia, F He, T Souho, L Lamboni… - Biomedicine & …, 2021 - Elsevier
The ongoing pandemic caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has drawn the attention of researchers and clinicians from several disciplines …

Experience with tocilizumab in severe COVID-19 pneumonia after 80 days of follow-up: A retrospective cohort study

O Moreno-Pérez, M Andres, JM Leon-Ramirez… - Journal of …, 2020 - Elsevier
Objectives To describe the clinical characteristics and predictors of major outcomes in
patients treated with tocilizumab (TCZ) for severe COVID-19 pneumonia. Patients and …

Immunopathogenesis of coronavirus-induced acute respiratory distress syndrome (ARDS): potential infection-associated hemophagocytic lymphohistiocytosis

C Quan, C Li, H Ma, Y Li, H Zhang - Clinical Microbiology Reviews, 2020 - Am Soc Microbiol
The outbreak of coronavirus disease 2019 (COVID-19) in December 2019 in Wuhan, China,
introduced the third highly pathogenic coronavirus into humans in the 21st century. Scientific …

Environmental impact assessment of COVID-19 therapeutic solutions. A prospective analysis

JV Tarazona, M Martínez, MA Martínez… - Science of The Total …, 2021 - Elsevier
Several medicinal products for human use are currently under consideration as potential
treatment for COVID-19 pandemic. As proposals cover also prophylactic use, the treatment …

HIF‐1, the Warburg Effect, and Macrophage/Microglia Polarization Potential Role in COVID‐19 Pathogenesis

E Ferraro, M Germanò, R Mollace… - Oxidative Medicine …, 2021 - Wiley Online Library
Despite the international scientific community's commitment to improve clinical knowledge
about coronavirus disease 2019 (COVID‐19), knowledge regarding molecular details …

Interleukin-1 in COVID-19 Infection: Immunopathogenesis and Possible Therapeutic Perspective

A Mardi, S Meidaninikjeh, S Nikfarjam… - Viral …, 2021 - liebertpub.com
The newfound coronavirus disease 2019 (COVID-19), initiated by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), is an international public health concern …

Cyclosporine A plus low‐dose steroid treatment in COVID‐19 improves clinical outcomes in patients with moderate to severe disease: A pilot study

JL Galvez‐Romero, O Palmeros‐Rojas… - Journal of internal …, 2021 - Wiley Online Library
Background COVID‐19 pandemic causes high global morbidity and mortality and better
medical treatments to reduce mortality are needed. Objective To determine the added …