Background There is heightened interest in how real-world data (RWD) can be used to
supplement or replace traditional mechanisms for collecting clinical information. A critical …

Children have historically been underrepresented or, indeed, omitted entirely, in drug trials,
leading to a relative dearth of evidence in support of appropriate drug treatments for many …

Background: Substantial improvements have been achieved with percutaneous coronary
intervention (PCI) for the treatment of Acute Coronary Syndromes (ACS). Nevertheless …

Background Randomized controlled trials (RCTs) in children with heart disease are
challenging and therefore infrequently performed. We sought to improve feasibility of …

Objective: The aim of this work was to study sex differences in major bleeding risk in relation
to dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) for acute …

Over the past several years, the transradial approach (TRA) for cardiac catheterization has
become increasingly adopted in the United States. The increased utilization of the TRA is …

Guidelines recommend managing patients aged≥ 75 with non-ST-segment elevation
myocardial infarction (NSTEMI) similar to younger patients. We analyze disparities in …

Background The radial artery is increasingly used for cardiac procedures, but is a relatively
small vessel that is prone to spasm when instrumented. Intra-arterial nitroglycerine has been …

Minority patients such as Blacks, Hispanics, and Native Americans are disproportionately
impacted by critical limb ischemia and amputation due to multiple factors such as …

Objectives To evaluate several techniques to reduce crossover rates in wrist artery access in
patients undergoing cardiac catheterization (CC)/percutaneous coronary intervention (PCI) …