Osteoporosis, a metabolic bone disease characterized by low bone mineral density and
deterioration of bone microarchitecture, has led to a high risk of fatal osteoporotic fractures …

Clearance of amyloid-beta (Aβ) from the brain is impaired in both early-onset and late-onset
Alzheimer's disease (AD). Mechanisms for clearing cerebral Aβ include proteolytic …

Objectives Medication‐related osteonecrosis of the jaw (MRONJ) is a severe adverse effect
of antiresorptive and/or antiangiogenic agents. As the treatment application for MRONJ is …

The present study aimed to purify and identify osteogenic peptides from sea cucumber
intestine hydrolysates (Mw< 3kDa) and further evaluate their pro-osteogenesis properties on …

Gain-of-function mutations in the low-density lipoprotein receptor-related protein 5 (LRP5)
can cause high-bone-mass (HBM) phenotype, with 19 identified mutations so far. The A242T …

Abstract Ca 2+/calmodulin-dependent protein kinase kinase 2 (CaMKK2) is a multi-
functional, serine/threonine protein kinase with predominant roles in inflammation, systemic …

Stress fractures, a common overuse injury in physically active individuals, present a
significant challenge for athletes and military personnel. Patients who sustain stress …

We aim was to present a case of severe osteoporosis with concern to an adult female who
was under specific medication against the condition while she experienced inexplicable …

In recent years, with the continuous development of biotechnology and medical science and
technology, therapeutic antibodies, as new biologics, have shown great potential and have …

Il meccanismo d'azione di romosozumab, anticorpo monoclonale umanizzato contro la
sclerostina, si basa sull'inibizione della glicoproteina sclerostina principalmente prodotta …