BNT162b2 induces robust cross-variant SARS-CoV-2 immunity in children

YC Bartsch, JW Chen, J Kang, MD Burns, KJ St Denis… - npj Vaccines, 2022 - nature.com
Currently available mRNA vaccines are extremely safe and effective to prevent severe
SARS-CoV-2 infections. However, the emergence of variants of concerns (VOCs) has …

A booster of Delta-Omicron RBD-dimer protein subunit vaccine augments sera neutralization of Omicron sub-variants BA. 1/BA. 2/BA. 2.12. 1/BA. 4/BA. 5

M Duan, H Duan, Y An, T Zheng, S Wan… - Emerging Microbes & …, 2023 - Taylor & Francis
ABSTRACT The SARS-CoV-2 Omicron variants of concern (VOCs) showed severe
resistance to the early-approved COVID-19 vaccines-induced immune responses. The …

COVID-19 vaccines: Update of the vaccines in use and under development

RA Marta, GEK Nakamura, B de Matos Aquino… - Vacunas, 2022 - Elsevier
The ongoing COVID-19 pandemic has imposed a series of challenges on the scientific
community. One of the biggest was the development of safe and effective vaccines in record …

RSV A2-based prefusion F vaccine candidates induce RSV A and RSV B cross binding and neutralizing antibodies and provide protection against RSV A and RSV B …

F Cox, E Saeland, A Thoma, W van den Hoogen… - Vaccines, 2023 - mdpi.com
RSV is divided into two antigenic subtypes, RSV A and RSV B, which is largely based on the
variation in the G protein, while the fusion protein F is more conserved and a target for …

Ad5‐nCoV booster and Omicron variant breakthrough infection following two doses of inactivated vaccine elicit comparable antibody levels against Omicron variants

W Kong, Q Zhong, M Chen, P Yu, R Xu… - Journal of Medical …, 2023 - Wiley Online Library
Little information is available for antibody levels against SARS‐CoV‐2 variants of concern
induced by Omicron breakthrough infection and a third booster with an inactivated vaccine …

[HTML][HTML] Sars-Cov-2—the role of natural immunity: A narrative review

S Diani, E Leonardi, A Cavezzi, S Ferrari… - Journal of clinical …, 2022 - mdpi.com
Background: Both natural immunity and vaccine-induced immunity to COVID-19 may be
useful to reduce the mortality/morbidity of this disease, but still a lot of controversy exists …

Cross-protection induced by highly conserved human B, CD4+, and CD8+ T-cell epitopes-based vaccine against severe infection, disease, and death caused by …

S Prakash, NR Dhanushkodi, L Zayou… - Frontiers in …, 2024 - frontiersin.org
Background The coronavirus disease 2019 (COVID-19) pandemic has created one of the
largest global health crises in almost a century. Although the current rate of Severe acute …

Mucosal prime-boost immunization with live murine pneumonia virus-vectored SARS-CoV-2 vaccine is protective in macaques

JA Kaiser, CE Nelson, X Liu, HS Park… - Nature …, 2024 - nature.com
Immunization via the respiratory route is predicted to increase the effectiveness of a SARS-
CoV-2 vaccine. Here, we evaluate the immunogenicity and protective efficacy of one or two …

Vaccine models predict rules for updating vaccines against evolving pathogens such as SARS-CoV-2 and influenza in the context of pre-existing immunity

R Desikan, SL Linderman, C Davis… - Frontiers in …, 2022 - frontiersin.org
Currently, vaccines for SARS-CoV-2 and influenza viruses are updated if the new vaccine
induces higher antibody-titers to circulating variants than current vaccines. This approach …

[HTML][HTML] Heterologous boost with mRNA vaccines against SARS-CoV-2 Delta/Omicron variants following an inactivated whole-virus vaccine

C Lu, Y Zhang, X Liu, F Hou, R Cai, Z Yu, F Liu… - Antiviral Research, 2023 - Elsevier
The coronavirus SARS-CoV-2 has mutated quickly and caused significant global damage.
This study characterizes two mRNA vaccines ZSVG-02 (Delta) and ZSVG-02-O (Omicron …