Non-coding RNAs expression in SARS-CoV-2 infection: pathogenesis, clinical significance, and therapeutic targets

X Liu, W Xiong, M Ye, T Lu, K Yuan, S Chang… - … and Targeted Therapy, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has been looming globally for
three years, yet the diagnostic and treatment methods for COVID-19 are still undergoing …

Different neutralization profiles after primary SARS-CoV-2 Omicron BA. 1 and BA. 2 infections

I Medits, DN Springer, M Graninger, JV Camp… - Frontiers in …, 2022 - frontiersin.org
Background and Methods The SARS-CoV-2 (severe acute respiratory syndrome
coronavirus 2) Omicron (B. 1.1. 529) variant is the antigenically most distinct variant to date …

Vaccine design via antigen reorientation

D Xu, JJ Carter, C Li, A Utz, PAB Weidenbacher… - Nature Chemical …, 2024 - nature.com
A major challenge in creating universal influenza vaccines is to focus immune responses
away from the immunodominant, variable head region of hemagglutinin (HA-head) and …

Reduced airborne transmission of SARS-CoV-2 BA. 1 Omicron virus in Syrian hamsters

ACM Boon, TL Darling, PJ Halfmann, J Franks… - PLoS …, 2022 - journals.plos.org
Since the start of the COVID-19 pandemic, Severe Acute Respiratory Syndrome Coronavirus
2 (SARS-CoV-2) has caused hundreds of millions of infections worldwide with more than 6.5 …

Humoral immune responses associated with control of SARS-CoV-2 breakthrough infections in a vaccinated US military population

GD Gromowski, CM Cincotta, S Mayer, J King… - …, 2023 - thelancet.com
Background COVID-19 vaccines have been critical for protection against severe disease
following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) but …

A biophysical model of viral escape from polyclonal antibodies

TC Yu, ZT Thornton, WW Hannon, WS DeWitt… - Virus …, 2022 - academic.oup.com
A challenge in studying viral immune escape is determining how mutations combine to
escape polyclonal antibodies, which can potentially target multiple distinct viral epitopes …

[HTML][HTML] Liquid-liquid phase separation of nucleocapsid proteins during SARS-CoV-2 and HIV-1 replication

BA Chau, V Chen, AW Cochrane, LJ Parent… - Cell Reports, 2023 - cell.com
The leap of retroviruses and coronaviruses from animal hosts to humans has led to two
ongoing pandemics and tens of millions of deaths worldwide. Retrovirus and coronavirus …

[HTML][HTML] Human early syncytiotrophoblasts are highly susceptible to SARS-CoV-2 infection

D Ruan, ZW Ye, S Yuan, Z Li, W Zhang, CP Ong… - Cell Reports …, 2022 - cell.com
Direct in vivo investigation of human placenta trophoblast's susceptibility to SARS-CoV-2 is
challenging. Here we report that human trophoblast stem cells (hTSCs) and their derivatives …

SARS-CoV-2 variant vaccine boosters trial: preliminary analyses

AR Branche, NG Rouphael, DJ Diemert, AR Falsey… - MedRxiv, 2022 - medrxiv.org
ABSTRACT Background Protection from SARS-CoV-2 vaccines wanes over time and is
compounded by emerging variants including Omicron subvariants. This study evaluated …

SARS-CoV-2-infection-and vaccine-induced antibody responses are long lasting with an initial waning phase followed by a stabilization phase

K Srivastava, JM Carreño, C Gleason, B Monahan… - Immunity, 2024 - cell.com
It is thought that mRNA-based vaccine-induced immunity to severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) wanes quickly, based mostly on short-term studies …