Kinetics and durability of humoral responses to SARS-CoV-2 infection and vaccination

K Srivastava, JM Carreno Quiroz, C Gleason… - medRxiv, 2023 - medrxiv.org
We analyzed the kinetics and durability of the humoral responses to severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection and vaccination using> 8,000 longitudinal …

Interface‐Guided Computational Protein Design Reveals Bebtelovimab‐Resistance Mutations in SARS‐CoV‐2 RBD: Correlation with Global Viral Genomes and …

S Maurya, S Kumar, AK Padhi - ChemistrySelect, 2023 - Wiley Online Library
The emergence of novel mutations in the SARS‐CoV‐2 spike protein challenges
monoclonal antibody (mAb) effectiveness. Comprehending resistance mutations and …

[HTML][HTML] Galectin-9 protects humanized-ACE2 immunocompetent mice from SARS-CoV-2 infection

ST Yeung, TA Premeaux, L Du, T Niki, SK Pillai… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 remains a global health crisis even with effective vaccines and the availability
of FDA approved therapies. Efforts to understand the complex disease pathology and …

[HTML][HTML] Human Fc-conjugated receptor binding domain-based recombinant subunit vaccines with short linker induce potent neutralizing antibodies against multiple …

L Chen, X Qi, D Liang, G Li, X Peng, X Li, B Ke… - Vaccines, 2022 - mdpi.com
The coronavirus disease-19 (COVID-19) pandemic has been ongoing since December
2019, with more than 6.3 million deaths reported globally as of August 2022. Despite the …

[HTML][HTML] Health influence of SARS-CoV-2 (COVID-19) on cancer: a review: Health influence of SARS-CoV-2 (COVID-19) on cancer

R Parise, YE Li, RM Nadar, S Ramesh… - Acta Biochimica et …, 2022 - ncbi.nlm.nih.gov
The novel coronavirus, namely, SARS-CoV-2 (COVID-19), broke out two years ago and has
caused major global health issues. Adequate treatment options are still lacking for the …

A systems approach evaluating the impact of SARS-CoV-2 variant of concern mutations on CD8+ T cell responses

PR Buckley, CH Lee, A Antanaviciute… - Immunotherapy …, 2023 - academic.oup.com
T cell recognition of SARS-CoV-2 antigens after vaccination and/or natural infection has
played a central role in resolving SARS-CoV-2 infections and generating adaptive immune …

Limited correlation between SARS-CoV-2 serologic assays for identification of high-titer COVID-19 convalescent plasma using FDA thresholds

NE Larkey, R Ewaisha, MA Lasho… - Microbiology …, 2022 - Am Soc Microbiol
ABSTRACT In August 2020, the Food and Drug Administration (FDA) Emergency Use
Authorization (EUA) for COVID-19 convalescent plasma (CCP) specified 12 authorized …

[HTML][HTML] SARS-CoV-2 Monitoring in Wastewater Reveals Novel Variants and Biomarkers of Infection

J McGowan, M Borucki, H Omairi, M Varghese… - Viruses, 2022 - mdpi.com
Wastewater-based epidemiology (WBE) is a popular tool for the early indication of
community spread of infectious diseases. WBE emerged as an effective tool during the …

An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo

K Liu, M Tang, W Xu, X Meng, H Jin… - Proceedings of the …, 2023 - National Acad Sciences
The classical manifestation of COVID-19 is pulmonary infection. After host cell entry via
human angiotensin–converting enzyme II (hACE2), the severe acute respiratory syndrome …

[HTML][HTML] Direct comparison of SARS-CoV-2 variant specific neutralizing antibodies in human and hamster sera

A Rössler, A Netzl, L Knabl, SH Wilks, B Mühlemann… - npj Vaccines, 2024 - nature.com
Antigenic characterization of newly emerging SARS-CoV-2 variants is important to assess
their immune escape and judge the need for future vaccine updates. To bridge data …