Advances in SARS-CoV-2 receptor-binding domain-based COVID-19 vaccines
ABSTRACT Introduction The Coronavirus Disease 2019 (COVID-19) pandemic has caused
devastating human and economic costs. Vaccination is an important step in controlling the …
devastating human and economic costs. Vaccination is an important step in controlling the …
Imprinted antibody responses against SARS-CoV-2 Omicron sublineages
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry
distinct spike mutations resulting in escape from antibodies induced by previous infection or …
distinct spike mutations resulting in escape from antibodies induced by previous infection or …
SARS-CoV-2 spike conformation determines plasma neutralizing activity elicited by a wide panel of human vaccines
JE Bowen, YJ Park, C Stewart, JT Brown… - Science …, 2022 - science.org
Numerous safe and effective coronavirus disease 2019 vaccines have been developed
worldwide that use various delivery technologies and engineering strategies. We show here …
worldwide that use various delivery technologies and engineering strategies. We show here …
[HTML][HTML] From Immunogen to COVID-19 vaccines: Prospects for the post-pandemic era
G Miao, Z Chen, H Cao, W Wu, X Chu, H Liu… - Biomedicine & …, 2023 - Elsevier
The COVID-19 pandemic has affected millions of people and posed an unprecedented
burden on healthcare systems and economies worldwide since the outbreak of the COVID …
burden on healthcare systems and economies worldwide since the outbreak of the COVID …
Broadly neutralizing antibodies against sarbecoviruses generated by immunization of macaques with an AS03-adjuvanted COVID-19 vaccine
The rapid emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
variants that evade immunity elicited by vaccination has placed an imperative on the …
variants that evade immunity elicited by vaccination has placed an imperative on the …
Multi-omics analysis of mucosal and systemic immunity to SARS-CoV-2 after birth
The dynamics of immunity to infection in infants remain obscure. Here, we used a multi-
omics approach to perform a longitudinal analysis of immunity to severe acute respiratory …
omics approach to perform a longitudinal analysis of immunity to severe acute respiratory …
Durability of immune responses to mRNA booster vaccination against COVID-19
PS Arunachalam, L Lai, H Samaha… - The Journal of …, 2023 - Am Soc Clin Investig
Background Maintaining durable immunity following vaccination represents a major
challenge, but whether mRNA booster vaccination improves durability is unknown. Methods …
challenge, but whether mRNA booster vaccination improves durability is unknown. Methods …
AS03 adjuvant enhances the magnitude, persistence, and clonal breadth of memory B cell responses to a plant-based COVID-19 vaccine in humans
Vaccine adjuvants increase the breadth of serum antibody responses, but whether this is
due to the generation of antigen-specific B cell clones with distinct specificities or the …
due to the generation of antigen-specific B cell clones with distinct specificities or the …
Synthetic multiantigen MVA vaccine COH04S1 and variant-specific derivatives protect Syrian hamsters from SARS-CoV-2 Omicron subvariants
F Wussow, M Kha, T Kim, M Ly, M Yll-Pico, S Kar… - npj Vaccines, 2023 - nature.com
Abstract Emerging SARS-CoV-2 Omicron subvariants continue to disrupt COVID-19 vaccine
efficacy through multiple immune mechanisms including neutralizing antibody evasion. We …
efficacy through multiple immune mechanisms including neutralizing antibody evasion. We …
Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants
The emergence of highly transmissible severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variants of concern (VOCs) that are resistant to the current COVID-19 …
(SARS-CoV-2) variants of concern (VOCs) that are resistant to the current COVID-19 …