COVID-19 and risk of acute ischemic stroke and acute lung injury in patients with type ii diabetes mellitus: the anti-inflammatory role of metformin

HM Al-Kuraishy, AI Al-Gareeb, M Alblihed… - Frontiers in …, 2021 - frontiersin.org
Background: Coronavirus disease 19 (COVID-19) is regarded as an independent risk factor
for acute ischemic stroke (AIS) due to the induction of endothelial dysfunction, coagulopathy …

[HTML][HTML] SARS-CoV-2 Nsp5 activates NF-κB pathway by upregulating SUMOylation of MAVS

W Li, J Qiao, Q You, S Zong, Q Peng, Y Liu… - Frontiers in …, 2021 - frontiersin.org
The COVID-19 is an infectious disease caused by SARS-CoV-2 infection. A large number of
clinical studies found high-level expression of pro-inflammatory cytokines in patients …

[HTML][HTML] Cellular immune response to COVID-19 and potential immune modulators

X Zhou, Q Ye - Frontiers in immunology, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Droplets and contacts serve as …

Therapeutic monoclonal antibodies for COVID-19 management: an update

VP Chavda, R Prajapati, D Lathigara… - Expert opinion on …, 2022 - Taylor & Francis
Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
affected more than 529 million people, and today the world is facing different mutant strains …

Nanocarrier vaccines for SARS-CoV-2

J Machhi, F Shahjin, S Das, M Patel… - Advanced Drug Delivery …, 2021 - Elsevier
The SARS-CoV-2 global pandemic has seen rapid spread, disease morbidities and death
associated with substantive social, economic and societal impacts. Treatments rely on re …

[PDF][PDF] Longitudinal metabolomics of human plasma reveals prognostic markers of COVID-19 disease severity

M Sindelar, E Stancliffe, M Schwaiger-Haber… - Cell Reports …, 2021 - cell.com
There is an urgent need to identify which COVID-19 patients will develop life-threatening
illness so that medical resources can be optimally allocated and rapid treatment can be …

COVID‐19 immunopathology: from acute diseases to chronic sequelae

M Arish, W Qian, H Narasimhan… - Journal of medical …, 2023 - Wiley Online Library
The clinical manifestation of coronavirus disease 2019 (COVID‐19) mainly targets the lung
as a primary affected organ, which is also a critical site of immune cell activation by severe …

Emerging roles of SARS-CoV-2 Spike-ACE2 in immune evasion and pathogenesis

CT Baldari, A Onnis, E Andreano, G Del Giudice… - Trends in …, 2023 - cell.com
The COVID-19 pandemic, caused by the SARS-CoV-2 virus, has caused an estimated 5
billion infections and 20 million deaths by respiratory failure. In addition to the respiratory …

[HTML][HTML] Herbal remedies, nutraceuticals, and dietary supplements for COVID-19 management: an update

VP Chavda, AB Patel, D Vihol, DD Vaghasiya… - Clinical Complementary …, 2022 - Elsevier
Currently, the world is facing a Coronavirus pandemic with a grave deficiency of specific
therapy for Coronavirus Disease (COVID-19). Moreover, scientists attempt to discover the …

The association between TNF-α, IL-6, and vitamin D levels and COVID-19 severity and mortality: a systematic review and meta-analysis

C Halim, AF Mirza, MI Sari - Pathogens, 2022 - mdpi.com
Background: An increasing number of scientific journals have proposed a connection
between tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6) and the severity of COVID …