A single transcription factor facilitates an insect host combating Bacillus thuringiensis infection while maintaining fitness

Z Guo, L Guo, J Qin, F Ye, D Sun, Q Wu, S Wang… - Nature …, 2022 - nature.com
Maintaining fitness during pathogen infection is vital for host survival as an excessive
response can be as detrimental as the infection itself. Fitness costs are frequently associated …

Induction of exaggerated cytokine production in human peripheral blood mononuclear cells by a recombinant SARS-CoV-2 spike glycoprotein S1 and its inhibition by …

OA Olajide, VU Iwuanyanwu, I Lepiarz-Raba… - Inflammation, 2021 - Springer
An understanding of the pathological inflammatory mechanisms involved in SARS-CoV-2
virus infection is necessary in order to discover new molecular pharmacological targets for …

[HTML][HTML] Increased LPS levels coexist with systemic inflammation and result in monocyte activation in severe COVID-19 patients

PC Teixeira, GP Dorneles, PC Santana Filho… - International …, 2021 - Elsevier
Mucosal barrier alterations may play a role in the pathogenesis of several diseases,
including COVID-19. In this study we evaluate the association between bacterial …

[HTML][HTML] COVID-19 and glomerular diseases

N Klomjit, L Zand, LD Cornell, MP Alexander - Kidney International Reports, 2023 - Elsevier
Abstract COVID (Coronavirus disease)-19 is a systemic disease and the kidney is one of the
target organs of infection. Kidney injury is common and can occur in up to 40% of patients …

Potent SARS-CoV-2-specific T cell immunity and low anaphylatoxin levels correlate with mild disease progression in COVID-19 patients

E Lafon, G Diem, C Witting, V Zaderer… - Frontiers in …, 2021 - frontiersin.org
T cells play a fundamental role in the early control and clearance of many viral infections of
the respiratory system. In SARS-CoV-2-infected individuals, lymphopenia with drastically …

Coronavirus disease 2019 (COVID‐19) update: From metabolic reprogramming to immunometabolism

M Rudiansyah, SA Jasim… - Journal of Medical …, 2022 - Wiley Online Library
The field of immunometabolism investigates and describes the effects of metabolic rewiring
in immune cells throughout activation and the fates of these cells. Recently, it has been …

SARS-CoV-2 neuronal invasion and complications: potential mechanisms and therapeutic approaches

O Swain, SK Romano, R Miryala, J Tsai… - Journal of …, 2021 - Soc Neuroscience
Clinical reports suggest that the coronavirus disease-19 (COVID-19) pandemic caused by
severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) has not only taken …

Recent advances in covalent organic frameworks for cancer diagnosis and therapy

AR Bagheri, C Li, X Zhang, X Zhou, N Aramesh… - Biomaterials …, 2021 - pubs.rsc.org
In recent years, the number of patients diagnosed with cancer has been soaring. Therefore,
the design, development, and implementation of new approaches for the diagnosis and …

[HTML][HTML] Lymphopenia as a predictor for adverse clinical outcomes in hospitalized patients with COVID-19: a single center retrospective study of 4485 cases

J Niu, C Sareli, D Mayer, A Visbal, A Sareli - Journal of Clinical Medicine, 2022 - mdpi.com
JCM | Free Full-Text | Lymphopenia as a Predictor for Adverse Clinical Outcomes in
Hospitalized Patients with COVID-19: A Single Center Retrospective Study of 4485 Cases …

Multipurpose advanced split T7 promoter-based transcription amplification for ultrasensitive molecular diagnostics

J Shin, T Yoon, D Nam, D Kim, S Kim, BS Cha… - Chemical Engineering …, 2023 - Elsevier
An accurate, convenient, and rapid diagnostic platform, which can be applied in facility-
limited or point-of-care (POC) settings, is essential to help prevent the spread of infectious …