Spatial transcriptomics data and analytical methods: an updated perspective

S Khan, JJ Kim - Drug Discovery Today, 2024 - Elsevier
Spatial transcriptomics (ST) is a newly emerging field that integrates high-resolution imaging
and transcriptomic data to enable the high-throughput analysis of the spatial localization of …

Spatially Resolved Single-Cell Omics: Methods, Challenges, and Future Perspectives

FS Dezem, NS Morosini, W Arjumand… - Annual Review of …, 2024 - annualreviews.org
Overlaying omics data onto spatial biological dimensions has been a promising technology
to provide high-resolution insights into the interactome and cellular heterogeneity relative to …

[HTML][HTML] STEM enables mapping of single-cell and spatial transcriptomics data with transfer learning

M Hao, E Luo, Y Chen, Y Wu, C Li, S Chen… - Communications …, 2024 - nature.com
Profiling spatial variations of cellular composition and transcriptomic characteristics is
important for understanding the physiology and pathology of tissues. Spatial transcriptomics …

[HTML][HTML] SRT-Server: powering the analysis of spatial transcriptomic data

S Yang, X Zhou - Genome Medicine, 2024 - Springer
Background Spatial resolved transcriptomics (SRT) encompasses a rapidly developing set
of technologies that enable the measurement of gene expression in tissue while retaining …

[HTML][HTML] SCAN: Spatiotemporal Cloud Atlas for Neural cells

Y Deng, Y Lu, M Li, J Shen, S Qin… - Nucleic Acids …, 2024 - academic.oup.com
The nervous system is one of the most complicated and enigmatic systems within the animal
kingdom. Recently, the emergence and development of spatial transcriptomics (ST) and …

An AI Agent for Fully Automated Multi-omic Analyses

J Zhou, B Zhang, X Chen, H Li, X Xu, S Chen, W He… - bioRxiv, 2023 - biorxiv.org
With the fast-growing and evolving omics data, the demand for streamlined and adaptable
tools to handle the bioinformatics analysis continues to grow. In response to this need, we …

Unsupervised feature selection based on the hidden knowledge of the Two-Dimensional Principal Component Analysis feature extraction method

F Beiranvand, V Mehrdad, MB Dowlatshahi - 2024 - researchsquare.com
In this paper, we proposed a new matrix-based feature selection method that used the
hidden knowledge in the orthogonal features obtained from the two-dimensional principal …

[引用][C] ShinySRT: shareable and interactive visualization of spatially resolved data

Z Pan, R Zhou, Y Wang - Journal of genetics and …, 2024 - pubmed.ncbi.nlm.nih.gov
ShinySRT: shareable and interactive visualization of spatially resolved data ShinySRT:
shareable and interactive visualization of spatially resolved data J Genet Genomics. 2024 …