Ankylosing spondylitis is a common inflammatory rheumatic disease that affects the axial
skeleton, causing characteristic inflammatory back pain, which can lead to structural and …

Spondyloarthropathies are a cluster of interrelated and overlapping chronic inflammatory
rheumatic diseases that primarily include ankylosing spondylitis, reactive arthritis, and the …

Background Treatment options for patients with ankylosing spondylitis are few. We aimed to
assess the effectiveness of infliximab, an antibody to tumour necrosis factor (TNF)-α, in …

Objective To study the relationship between spinal mobility, radiographic damage of the
spine and spinal inflammation as assessed by MRI in patients with ankylosing spondylitis …

In a search of new bone proteins, the glycoprotein YKL-40 was identified in 1989 to be
secreted in vitro in large amount by the human osteosarcoma cell line MG63. The protein …

Objective The aim of this study was to define characteristic MRI findings in the spine of
patients with axial spondyloarthritis (SpA) and provide a definition of a positive spinal MRI …

Objective To evaluate a magnetic resonance imaging (MRI) scoring system for the
assessment of spinal inflammation in patients with ankylosing spondylitis (AS) who …

Objective There is increasing evidence that tumor necrosis factor α (TNFα) is centrally
involved in the pathogenesis of ankylosing spondylitis (AS) and other spondylarthritides …

Objective Tumor necrosis factor α (TNFα) has been detected in sacroiliac joint biopsy
specimens from patients with spondylarthropathy. The present open pilot study was …

Background: Structural changes such as erosions, syndesmophytes and ankylosis are
characteristic of ankylosing spondylitis (AS). These can be quantified by the modified Stokes …