Understanding how viruses and antibodies evolve in response to one another can help inform future vaccines and therapies. This project investigated longitudinal samples from …
The current globally dominant SARS-CoV-2 variants are showing immune escape and reduced susceptibility to antiviral drugs. Therefore, agencies responsible for drug evaluation …
V Gerardi, MA Rohaim, RFE Naggar, MO Atasoy… - 2023 - researchgate.net
The emergence of the Omicron variant has reinforced the importance of continued SARS- CoV-2 evolution and its possible impact on vaccine effectiveness. Specifically, mutations in …
J Hiscox, X Dong, D Matthews, G Gallo, A Darby… - 2023 - researchsquare.com
SARS-CoV-2 emerged in the human population in late 2019 1, 2, went through population bottlenecks 3 and has undergone adaptation and evolution by single nucleotide …
Background: Mutations among the structural proteins of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can lead to the emergence of new variants with different …
Molecular recognition between two or more molecular binding partners plays an essential role in many cellular processes and pathogen entry steps. It is widely accepted now that …
VM Tsvetov, IS Burashnikova, DA Sychev - Pharmateca, 2021 - bioethicsjournal.ru
Currently, there are prerequisites, such as data from phase 2 and 3 multicenter clinical trials, to recommend sotrovimab and bamlanivimab+ etesevimab at the prehospital stage for …