Severe covid-19 pneumonia has posed critical challenges for the research and medical
communities. Older age, male sex, and comorbidities increase the risk for severe disease …

This review summarises the fundamental pathophysiological features of COVID-19 in the
context of the respiratory system. It provides an overview of the key clinical manifestations of …

Cyclic guanosine monophosphate (cGMP), an important intracellular second messenger,
mediates cellular functional responses in all vital organs. Phosphodiesterase 5 (PDE5) is …

Purpose This study aimed at investigating the mechanisms underlying the oxygenation
response to proning and recruitment maneuvers in coronavirus disease 2019 (COVID-19) …

The impact of the global health crisis due to the virus Severe Acute Respiratory Syndrome
Coronavirus-2 (SARS-CoV-2)-the causative pathogen of the coronavirus disease 2019 …

New Findings What is the topic of this review? This review presents the fundamental
concepts of respiratory physiology and pathophysiology, with particular reference to lung …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is transmitted through
respiratory droplets, aerosols and close contact. Cross infections occur because viruses …

Objectives: The purpose of the present study was to assess and describe the severity of
symptoms reported by Covid-19 positive patients who vaped (smoked e-cigarettes) when …

Background SARS-CoV-2 seems to affect the regulation of pulmonary perfusion.
Hypoperfusion in areas of well-aerated lung parenchyma results in a ventilation–perfusion …

Infection with the novel severe acute respiratory coronavirus-2 (SARS-CoV2) results in
COVID-19, a disease primarily affecting the respiratory system to provoke a spectrum of …