The emergence of new pathogens and multidrug resistant bacteria is an important public
health issue that requires the development of novel classes of antibiotics. Antimicrobial …

During the development of antimicrobial peptides (AMP) as potential therapeutics,
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …

Biophysical and structural investigations are presented with a focus on the membrane lipid
interactions of cationic linear antibiotic peptides such as magainin, PGLa, LL37, and melittin …

Host‐defense peptides (HDPs) feature evolution‐tested potency against life‐threatening
pathogens. While piscidin 1 (p1) and piscidin 3 (p3) are homologous and potent fish HDPs …

Even 30 years after the discovery of magainins, biophysical and structural investigations on
how these peptides interact with membranes can still bear surprises and add new …

Piscidins are histidine-enriched antimicrobial peptides that interact with lipid bilayers as
amphipathic α-helices. Their activity at acidic and basic pH in vivo makes them promising …

The study of peptide-lipid and peptide-peptide interactions as well as their topology and
dynamics using biophysical and structural approaches have changed our view how …

Antimicrobial peptides (AMPs) are short molecules produced by almost all organisms. Fish
AMPs contain innate immune components as their primary immune molecules. The fish …

Antimicrobial peptides are short amphipathic peptides that are produced by the innate
immune system in order to protect a host from pathogens. They have been shown to have …

Multidrug combination therapies have been proven to be advantageous in combating the
proliferation of antibiotic-resistant bacterial pathogens in recent years, not only contributing …