Th17 cells play an important role in the abnormal immune response in inflammatory bowel
disease (IBD) and are involved in the development and progression of inflammation and …

Inflammatory bowel disease (IBD), comprising Crohn's disease (CD) and ulcerative colitis
(UC), is a heterogeneous state of chronic intestinal inflammation with no exact known cause …

Despite the great progress of current bacterially based biotherapeutics, their unsatisfying
efficacy and underlying safety problems have limited their clinical application. Herein …

Background In Crohn disease, differentiation between active intestinal inflammation and
fibrosis has implications for treatment, but current imaging modalities are not reliably …

The cortical actin cytoskeleton plays a critical role in maintaining intestinal epithelial
integrity, and the loss of this architecture leads to chronic inflammation, as seen in …

Ulcerative colitis (UC) is a chronic inflammatory bowel disease involving mainly the
colorectal mucosa and submucosa, the incidence of which has been on the rise in recent …

Abstract Background and Aims Ultrasound elastography [USE] is an innovative, non-
invasive, promptly available, ancillary technique that has been proposed in the evaluation of …

In recent years, the incidence of intestinal ischemia-reperfusion injury (II/RI), inflammatory
bowel disease (IBD), and colorectal cancer (CRC) has been gradually increasing, posing …

The human microbiome orchestrates a variety of metabolic, immunological and regulatory
functions in health and disease. However, experimentally dissecting host–microbiome …

Fibro-stenosing Crohn's disease (CD) is a common disease presentation that leads to
impaired quality of life and often requires endoscopic treatments or surgery. From a …