Background More than 70% of patients with type 2 diabetes (T2DM) concomitantly suffer
from Non-alcoholic fatty liver disease (NAFLD), and the coexistence and interaction of them …

Coumarin derivates have been proposed as a potential treatment for metabolic-dysfunction-
associated fatty liver disease (MAFLD). However, the mechanisms underlying their …

Background Non-alcoholic fatty liver disease (NAFLD) is a common metabolic liver disease
worldwide. It has been proven that aescin (Aes), a bioactive compound derived from the ripe …

Reactive oxygen species (ROS) are radical oxygen intermediates that serve as important
second messengers in signal transduction. However, when the accumulation of these …

Lipid metabolism disorders are a prominent characteristic in the pathological development
of non-alcoholic fatty liver disease (NAFLD). Danshen zexie decoction (DZD) is a Chinese …

Abstract Ethnopharmacological relevance Alpinia officinarum Hance, a perennial natural
medicine-food herb, has been traditionally used to treat colds, stomachache, and diabetes …

Nobiletin (NOB), a flavonoid with significant antioxidant potential, holds promise for treating
nonalcoholic fatty liver disease (NAFLD). In this work, we aim to assess the effects and …

Acylation of anthocyanin with fatty acid has been extensively applied for the improvement of
their lipophilicity and stability. However, their functionalities are not fully investigated. This …

Non-alcoholic fatty liver disease (NAFLD) is a metabolic disease closely associated with
dietary habits. Diosgenin is abundant in yam, a common food and traditional Chinese …

Piperine (PIP) is an alkaloid derived from peppercorns. Herein, we assessed its effects on
hepatocyte EMT and HSC activation in vitro and CCl4-elicited liver fibrosis in mice. Further …