[HTML][HTML] The role of HIF-1α/HO-1 pathway in hippocampal neuronal ferroptosis in epilepsy

Z Liang, Z Zheng, Q Guo, M Tian, J Yang, X Liu, X Zhu… - Iscience, 2023 - cell.com
Epilepsy, a common central nervous system disorder, remains an enigma in pathogenesis.
Emerging consensus designates hippocampal neuronal injury as a cornerstone for …

Integrative analysis of gut microbiota and fecal metabolites in metabolic associated fatty liver disease patients

L Yang, Y Dai, H He, Z Liu, S Liao, Y Zhang… - Frontiers in …, 2022 - frontiersin.org
Objective Metabolic associated fatty liver disease (MAFLD) affects nearly a quarter of the
world's population. Our study aimed to characterize the gut microbiome and overall changes …

Lipid-Lowering Effects of Inonotus obliquus Polysaccharide In Vivo and In Vitro

M Yang, D Hu, Z Cui, H Li, C Man, Y Jiang - Foods, 2021 - mdpi.com
Excessive lipid intake will cause hyperlipidemia, fatty liver metabolism disease, and
endanger people's health. Edible fungus polysaccharide is a natural active substance for …

[HTML][HTML] Natural and semi-synthetic flavonoid anti-SARS-CoV-2 agents for the treatment of long COVID-19 disease and neurodegenerative disorders of cognitive …

J Melrose, MM Smith - Frontiers in Bioscience-Elite, 2022 - imrpress.com
The aim of this review is to highlight the beneficial attributes of flavonoids, a diverse family of
widely-distributed polyphenolic phytochemicals that have beneficial cell and tissue …

Protective effect of traditional Chinese medicine on non-alcoholic fatty liver disease and liver cancer by targeting ferroptosis

Q Wu, Z Chen, Y Ding, Y Tang, Y Cheng - Frontiers in Nutrition, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease with high incidence and
is closely related to metabolic syndrome. If not controlled, it may eventually become …

Molecular Mechanisms of Fucoxanthin in Alleviating Lipid Deposition in Metabolic Associated Fatty Liver Disease

S Yang, J Li, L Yan, Y Wu, L Zhang, B Li… - Journal of Agricultural …, 2024 - ACS Publications
Metabolic-associated fatty liver disease (MAFLD) is witnessing a global surge; however, it
still lacks effective pharmacological interventions. Fucoxanthin, a natural bioactive …

Qingrequzhuo capsule alleviated methionine and choline deficient diet-induced nonalcoholic steatohepatitis in mice through regulating gut microbiota, enhancing gut …

S Lv, Z Zhang, X Su, W Li, X Wang, B Pan… - Frontiers in …, 2023 - frontiersin.org
Qingrequzhuo capsule (QRQZ), composed of Morus alba L., Coptis chinensis Franch.,
Anemarrhena asphodeloides Bunge, Alisma plantago-aquatica subsp. orientale (Sam.) …

Exploring the potential of treating chronic liver disease targeting the PI3K/Akt pathway and polarization mechanism of macrophages

Y Yang, X Jia, M Qu, X Yang, Y Fang, X Ying, M Zhang… - Heliyon, 2023 - cell.com
Chronic liver disease is a significant public health issue that can lead to considerable
morbidity and mortality, imposing an enormous burden on healthcare resources …

Pectolinarigenin attenuates hepatic ischemia/reperfusion injury via activation of the PI3K/AKT/Nrf2 signaling pathway

H Li, Y Chen, M Ding, Z Yan, W Guo, R Guo - Chemico-biological …, 2023 - Elsevier
Hepatic ischemia/reperfusion (I/R) injury is an unavoidable complication of liver
hepatectomy, transplantation, and systemic shock. Pectolinarigenin (Pec) is a flavonoid with …

Baicalein alleviates non-alcoholic fatty liver disease in mice by ameliorating intestinal barrier dysfunction

C Guo, Q Li, R Chen, W Fan, X Zhang, Y Zhang… - Food & Function, 2023 - pubs.rsc.org
Non-alcoholic fatty liver disease (NAFLD) is the main cause of chronic liver disease, and its
pathological development is closely related to the gut–liver axis. The intestinal barrier, an …