CircRNAs, covalently closed noncoding RNAs, are widely expressed in a wide range of
species ranging from viruses to plants to mammals. CircRNAs were enriched in the Wnt …

Transcription factor EB (TFEB) is considered the master transcriptional regulator of
autophagy and lysosomal biogenesis, which regulates target gene expression through …

Sex-determining region Y-box2 (SOX2), a master regulator of embryonic and induced
pluripotent stem cells, drives cancer stem cells (CSCs) properties, fuels tumor initiation, and …

The Wnt/β-catenin signaling pathway is a growth control pathway involved in various
biological processes as well as the development and progression of cancer. Colorectal …

Berberine (BBR), an isoquinoline alkaloid extracted from Coptidis Rhizoma, has a long
history of treating dysentery in the clinic. Over the past two decades, the polytrophic …

Colorectal cancer (CRC) is a disease with complex pathogenesis, it is prone to metastasis,
and its development involves abnormalities in multiple signaling pathways. Surgery …

Colorectal cancer (CRC) is one of the most common carcinomas. Although great progress
has been made in recent years, CRC survival remains unsatisfactory due to high metastasis …

Colorectal cancer (CRC) is a common malignant tumor of digestive system. Its incidence
rate and mortality rate ranks the third among all the malignant tumors. The objective of this …

The lncRNA PVT1 has emerged as a pivotal component in the intricate landscape of cancer
pathogenesis, particularly in lung cancer. PVT1, situated in the 8q24 chromosomal region …

The transcription factor MYB proto-oncogene like 2 (MYBL2) is critical in regulating gene
expression and tumorigenesis. However, the biological function of MYBL2 in bladder cancer …