Advances and opportunities in malaria population genomics

DE Neafsey, AR Taylor, BL MacInnis - Nature Reviews Genetics, 2021 - nature.com
Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …

[HTML][HTML] Biology of human malaria plasmodia including Plasmodium knowlesi

S Antinori, L Galimberti, L Milazzo… - … journal of hematology …, 2012 - ncbi.nlm.nih.gov
Malaria is a vector-borne infection caused by unicellular parasite of the genus Plasmodium.
Plasmodia are obligate intracellular parasites that are able to infect and replicate within the …

A single-cell atlas of Plasmodium falciparum transmission through the mosquito

E Real, VM Howick, FA Dahalan, K Witmer… - Nature …, 2021 - nature.com
Malaria parasites have a complex life cycle featuring diverse developmental strategies, each
uniquely adapted to navigate specific host environments. Here we use single-cell …

Mitosis in the human malaria parasite Plasmodium falciparum

N Gerald, B Mahajan, S Kumar - Eukaryotic cell, 2011 - Am Soc Microbiol
Malaria is caused by intraerythrocytic protozoan parasites belonging to Plasmodium
spp.(phylum Apicomplexa) that produce significant morbidity and mortality, mostly in …

Resolving the cause of recurrent Plasmodium vivax malaria probabilistically

AR Taylor, JA Watson, CS Chu, K Puaprasert… - Nature …, 2019 - nature.com
Relapses arising from dormant liver-stage Plasmodium vivax parasites (hypnozoites) are a
major cause of vivax malaria. However, in endemic areas, a recurrent blood-stage infection …

Mathematical modeling of climate change and malaria transmission dynamics: a historical review

SE Eikenberry, AB Gumel - Journal of mathematical biology, 2018 - Springer
Malaria, one of the greatest historical killers of mankind, continues to claim around half a
million lives annually, with almost all deaths occurring in children under the age of five living …

Wolbachia infections in natural Anopheles populations affect egg laying and negatively correlate with Plasmodium development

WR Shaw, P Marcenac, LM Childs, CO Buckee… - Nature …, 2016 - nature.com
The maternally inherited alpha-proteobacterium Wolbachia has been proposed as a tool to
block transmission of devastating mosquito-borne infectious diseases like dengue and …

Checks and balances? DNA replication and the cell cycle in Plasmodium

H Matthews, CW Duffy, CJ Merrick - Parasites & vectors, 2018 - Springer
It is over 100 years since the life-cycle of the malaria parasite Plasmodium was discovered,
yet its intricacies remain incompletely understood-a knowledge gap that may prove crucial …

A microsporidian impairs Plasmodium falciparum transmission in Anopheles arabiensis mosquitoes

JK Herren, L Mbaisi, E Mararo, EE Makhulu… - Nature …, 2020 - nature.com
A possible malaria control approach involves the dissemination in mosquitoes of inherited
symbiotic microbes to block Plasmodium transmission. However, in the Anopheles gambiae …

Plasmodium development in Anopheles: a tale of shared resources

WR Shaw, P Marcenac, F Catteruccia - Trends in Parasitology, 2022 - cell.com
Interactions between the Anopheles mosquito vector and Plasmodium parasites shape how
malaria is transmitted in endemic regions. The long association of these two organisms has …