Hemophagocytic lymphohistiocytosis

TS Ponnatt, CM Lilley, KM Mirza - Archives of Pathology & …, 2022 - meridian.allenpress.com
Context.—Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disorder of
immune regulation that can eventually result in end-organ damage and death. HLH is …

The effects of COVID-19 on the placenta during pregnancy

HS Rad, J Röhl, N Stylianou, MC Allenby… - Frontiers in …, 2021 - frontiersin.org
Coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has caused a global pandemic. The virus primarily affects the …

Haemophagocytic syndrome and COVID-19

S Retamozo, P Brito-Zerón, A Sisó-Almirall… - Clinical …, 2021 - Springer
Primary and secondary haemophagocytic lymphohistiocytosis (HLH) are hyperferritinaemic
hyperinflammatory syndromes with a common terminal pathway triggered by different …

Plasmacytoid dendritic cells depletion and elevation of IFN-γ dependent chemokines CXCL9 and CXCL10 in children with multisystem inflammatory syndrome

F Caldarale, M Giacomelli, E Garrafa… - Frontiers in …, 2021 - frontiersin.org
Background SARS-CoV-2 occurs in the majority of children as COVID-19, without symptoms
or with a paucisymptomatic respiratory syndrome, but a small proportion of children develop …

Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review

A Shafqat, S Shafqat, SA Salameh, J Kashir… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …

Do COVID-19 infections result in a different form of secondary hemophagocytic lymphohistiocytosis

R Chu, C van Eeden, S Suresh, WI Sligl… - International journal of …, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has resulted in significant morbidity and mortality …

Cytokine storm in severe COVID‐19 pneumonia

B Gürsoy, CD Sürmeli, M Alkan, C Satıcı… - Journal of Medical …, 2021 - Wiley Online Library
In this study, laboratorial parameters of hospitalized novel coronavirus (COVID‐19) patients,
who were complicated with severe pneumonia, were compared with the findings of cytokine …

Infection‐induced inflammation from specific inborn errors of immunity to COVID‐19

CL Ku, IT Chen, MZ Lai - The FEBS Journal, 2021 - Wiley Online Library
Inborn errors of immunity (IEIs) are a group of genetically defined disorders leading to
defective immunity. Some IEIs have been linked to mutations of immune receptors or …

Plasma Von Willebrand factor levels predict survival in COVID-19 patients across the entire spectrum of disease severity

VV Thomas, SE Kumar, V Alexander, A Nadaraj… - Indian Journal of …, 2021 - Springer
Background: Characterization of reticulo-endothelial activation in COVID-19 may guide
treatment. Objectives: To assess reticulo-endothelial activation and its correlation with …

Assessment of the HScore as a predictor of disease outcome in patients with COVID-19

M Bordbar, A Sanaei Dashti, A Amanati… - BMC Pulmonary …, 2021 - Springer
Abstract Severe coronavirus disease 2019 (COVID-19) accompanies hypercytokinemia,
similar to secondary hemophagocytic lymphohistiocytosis (sHLH). We aimed to find if …