Role of main RNA modifications in cancer: N6-methyladenosine, 5-methylcytosine, and pseudouridine

C Xue, Q Chu, Q Zheng, S Jiang, Z Bao, Y Su… - Signal transduction and …, 2022 - nature.com
Cancer is one of the major diseases threatening human life and health worldwide.
Epigenetic modification refers to heritable changes in the genetic material without any …

Exploring ncRNA-mediated regulation of EGFR signalling in glioblastoma: From mechanisms to therapeutics

R Thapa, M Afzal, A Goyal, G Gupta, AA Bhat… - Life sciences, 2024 - Elsevier
Glioblastoma (GBM) is the most prevalent and deadly primary brain tumor type, with a
discouragingly low survival rate and few effective treatments. An important function of the …

Long noncoding RNA ADAMTS9-AS1 represses ferroptosis of endometrial stromal cells by regulating the miR-6516-5p/GPX4 axis in endometriosis

Y Wan, C Gu, J Kong, J Sui, L Zuo, Y Song, J Chen - Scientific reports, 2022 - nature.com
Endometriosis (EMs) is one of the most frequent diseases of reproductive-age women and is
characterized by the growth of endometrial tissues beyond the uterus. The enhanced …

Long noncoding RNA SNHG4: A novel target in human diseases

Q Chu, X Gu, Q Zheng, Z Guo, D Shan, J Wang… - Cancer Cell …, 2021 - Springer
Recently, long noncoding RNAs (lncRNAs) have attracted great attention from researchers.
LncRNAs are non-protein-coding RNAs of more than 200 nucleotides in length. Multiple …

Molecular insights into regulatory RNAs in the cellular machinery

S Yang, SH Kim, E Yang, M Kang, JY Joo - Experimental & Molecular …, 2024 - nature.com
It is apparent that various functional units within the cellular machinery are derived from
RNAs. The evolution of sequencing techniques has resulted in significant insights into …

A ferroptosis-related lncRNAs signature predicts prognosis and therapeutic response of gastric cancer

S Xiao, X Liu, L Yuan, F Wang - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
Background: Accumulating literature demonstrates that long noncoding RNAs (lncRNAs) are
involved in ferroptosis and gastric cancer progression. However, the predictive value of …

Exploring ncRNA-mediated pathways in sepsis-induced pyroptosis

AA Bhat, Y Riadi, M Afzal, P Bansal, H Kaur… - … -Research and Practice, 2024 - Elsevier
Sepsis, a potentially fatal illness caused by an improper host response to infection, remains
a serious problem in the world of healthcare. In recent years, the role of ncRNA has …

The involvement of long non-coding RNAs in glioma: from early detection to immunotherapy

X Wu, L Yang, J Wang, Y Hao, C Wang… - Frontiers in …, 2022 - frontiersin.org
Glioma is a brain tumor that arises in the central nervous system and is categorized
according to histology and molecular genetic characteristics. Long non-coding RNAs …

Tumor-derived biomarkers in liquid biopsy of glioblastoma

V Khristov, A Lin, Z Freedman, J Staub, G Shenoy… - World neurosurgery, 2023 - Elsevier
There is a pressing clinical need for minimally invasive liquid biopsies to supplement
imaging in the treatment of glioblastoma. Diagnostic imaging is often difficult to interpret and …

Mitochondrial-targeted antioxidant MitoQ-mediated autophagy: a novel strategy for precise radiation protection

X Bao, X Liu, Q Wu, F Ye, Z Shi, D Xu, J Zhang, Z Dou… - Antioxidants, 2023 - mdpi.com
Radiotherapy (RT) is one of the most effective cancer treatments. However, successful
radiation protection for normal tissue is a clinical challenge. Our previous study observed …