Chronic kidney disease (CKD) patients have a higher risk of developing early
cardiovascular disease (CVD). Although vascular calcification (VC) is one of the strongest …

Objectives Vascular stiffness (VS) and vascular calcification (VC) are surrogate markers of
vascular health associated with cardiovascular events. Vitamin K-dependent proteins …

Purpose Vascular calcification (VC) is an independent risk factor for cardiovascular disease
in hemodialysis patients while Matrix GLA protein (MGP) is one of the most potent inhibitors …

Vitamin K is a cofactor for the function of the enzyme γ-glutamyl carboxylase, necessary for
the activation of multiple vitamin K dependent-proteins. Vitamin K dependent-proteins …

Vitamin K is involved many biological processes, such as the regulation of blood
coagulation, prevention of vascular calcification, bone metabolism and modulation of cell …

Patients with chronic kidney disease (CKD) are at increased risk of osteoporosis and
vascular calcification. Bone demineralization and vascular mineralization go often hand in …

Specific patient cohorts are at increased risk of vascular calcification. Functional matrix-gla
protein (MGP), a tissue-derived vitamin K dependent protein, is reported to be an important …

Background Vascular calcifications are highly prevalent in hemodialysis patients.
Dephosphorylated-uncarboxylated MGP (dp-ucMGP) was found to increase in vitamin K …

Abstract Purpose of Review Vitamin K is a fat-soluble vitamin required for the activation of
several vitamin K-dependent proteins to confer functioning. A growing body of evidence …

The objective of the present review was to summarize the molecular mechanisms
associated with the effects of the vitamins A, C, E and K, and group B vitamins on bone and …