Background: Systemic sclerosis (SSc) patients face an elevated risk of cardiovascular
disease (CVD), even when classic cardiovascular risk factors are considered. Plasma …

People with advanced chronic kidney disease (CKD) or end-stage kidney disease (ESKD)
commonly have altered metabolism or actions of many vitamins and abnormal vitamin …

Patients with chronic kidney disease (CKD) suffer disproportionately from a high burden of
cardiovascular disease, which, despite recent scientific advances, remains partly …

Background: A low vitamin K status is common in patients on haemodialysis, and this is
considered one of the reasons for the accelerated atherosclerosis in these patients. The …

Objective: This study evaluated associations of serum matrix Gla protein (MGP), plasma
vitamin K1, and plasma vitamin K2 with coronary artery calcium score (CACS) and …

The aim of this study was to evaluate the effects of vitamin K1 on various vitamin K-
dependent proteins in critically ill patients with prolonged Owren PT. We included critically ill …

Ectopic mineralization disorders comprise a broad spectrum of inherited or acquired
diseases characterized by aberrant deposition of calcium crystals in multiple organs, such …

Phosphate is essential for proper cell function by providing the fundamentals for DNA,
cellular structure, signaling and energy production. The homeostasis of phosphate is …

In Chronic Kidney Disease, vascular calcification (VC) is highly prevalent even at early
stages and is gradually enhanced, along with disease progression to End-Stage Renal …

One mechanism to regulate pathological vascular calcification (VC) is its active inhibition.
Loss or inactivation of endogenic inhibitors is a major inductor of VC. Such inhibitors are …