The beamline design, microscope specifications, and initial results from the new mid-
infrared beamline (IRENI) are reviewed. Synchrotron-based spectrochemical imaging, as …

Glycerophosphocholines are the major building blocks of biological membranes. They are
also precursors of low‐molecular‐weight second messengers with mass to charge ratios of …

Lipids are a major class of molecules that play key roles in different biological processes.
Understanding their biological roles and mechanisms remains analytically challenging due …

We have recently reported that a novel muscle-specific inositide phosphatase
(MIP/MTMR14) plays a critical role in [Ca 2+] i homeostasis through dephosphorylation of sn …

Nitric oxide (NO) signaling is inextricably linked to both its physical and chemical properties.
Due to its preferentially hydrophobic solubility, NO molecules tend to partition from the …

Lipidomics is a subspecialty of metabolomics that focuses on water insoluble metabolites
that form membrane barriers. Most lipidomic databases catalog lipids from common model …

Lipid analysis is a well-established field of research that focuses on one lipid or a few lipids.
The recent developments in mass spectrometry technologies have enabled more …

β-amyloid (Aβ) is produced by the β-secretase 1 (BACE1)-mediated enzymatic cleavage of
the amyloid precursor protein through the amyloidogenic pathway, making BACE1 a …

Bacterial resistance to antibiotics has become an increasing threat, requiring not only the
development of new targets in drug discovery, but more importantly, a better understanding …

The synaptic vesicle cycle requires a stringent interplay between many entities, traversing
through temporal and spatial coordination in order to ensure successful and sustainable …