Animals exposed to brief periods of moderate hypoxia (8% to 10% oxygen for 3 hours) are
protected against cerebral and cardiac ischemia between 1 and 2 days later. This hypoxia …

Thioredoxin is a small redox-regulating protein, which plays crucial roles in maintaining
cellular redox homeostasis and cell survival and is highly expressed in many cancers. The …

BACKGROUND: The pathophysiology of ischemic hepatitis, otherwise known as “shock
liver,” is poorly understood, although it is believed to be the result of a reduction in systemic …

Stroke is one of the leading causes of morbidity and mortality worldwide, and it is increasing
in prevalence. The limited therapeutic window and potential severe side effects prevent the …

The survival of all organisms depends upon their ability to overcome stressful conditions, an
ability that involves adaptive changes in cells and molecules. Findings from studies of …

Pre-conditioning by ischemia, hyperthermia, hypothermia, hyperbaric oxygen (and
numerous other modalities) is a rapidly growing area of investigation that is used in …

Neurons can be preconditioned by various procedures to resist ischemic events. The
preconditioning mechanism induced is characterized by a brief episode of ischemia that …

Background and Purpose—Hypoxia preconditioning (HPC), rapid or delayed, has been
reported to induce neuroprotection against subsequent severe stress. Because δ-opioid …

Background. In this study, we evaluated the beneficial effect of brief ischemia and
reperfusion, which was shown to have local effects on liver previously, on kidney as a …

Background/Aims: Ischemic preconditioning (IP) is known to protect hepatic tissue from
ischemia–reperfusion injury. However, the mechanisms involved are not fully understood …