Macrophage polarization is influenced by lipids, which also exert significant control over
macrophage functions. Lipids and their metabolites are players in intricate signaling …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disorder of unknown origin and
the most common interstitial lung disease. It progresses with the recruitment of fibroblasts …

Pulmonary fibrosis results from a plethora of abnormal pathogenetic events. In idiopathic
pulmonary fibrosis (IPF), inhalational, environmental, or occupational exposures in …

Idiopathic pulmonary fibrosis (IPF) is characterized by an aberrant repair response with
uncontrolled turnover of extracellular matrix involving mesenchymal cell phenotypes, where …

Idiopathic pulmonary fibrosis (IPF) is a lethal interstitial lung disease of unknown etiology
with a poor prognosis. It is a chronic and progressive disease that has a distinct radiological …

AgRP neurons drive hunger, and excessive nutrient intake is the primary driver of obesity
and associated metabolic disorders. While many factors impacting central regulation of …

Macrophages are highly heterogeneous and plastic, and have two main polarized
phenotypes that are determined by their microenvironment, namely pro-and anti …

Interstitial lung disease (ILD) is one of the most serious extra-articular complications of
rheumatoid arthritis (RA), which increases the mortality of RA. Because the pathogenesis of …

Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver
disease worldwide. NAFLD is prevalent in about 30% of people worldwide. The lack of …

Schistosomiasis is a serious and neglected disease with a high prevalence in tropical and
subtropical countries. The primary pathology of hepatic schistosomiasis caused by …