The hippocampus is one of a group of remarkable structures embedded within the brain's
medial temporal lobe. Long known to be important for memory, it has been a prime focus of …

The mechanisms involved in plasticity in the nervous system are thought to support
cognition, and some of these processes are affected during normal ageing. Notably …

Place cells of the rodent hippocampus constitute one of the most striking examples of a
correlation between neuronal activity and complex behaviour in mammals,. These cells …

The contribution of glutamate to synaptic transmission, plasticity and development is well
established; current evidence is based on diverse approaches to decipher function and …

Episodic and spatial memories each involve the encoding of complex associations in
hippocampal neuronal circuits. Such memory traces could be stabilised from short-to long …

Five key topics have been reverberating in hippocampal‐entorhinal cortex (EC) research
over the past five decades: episodic and semantic memory, path integration (“dead …

This review charts recent advances from a variety of disciplines that create a new
perspective on why the multiple hippocampal–anterior thalamic interconnections are …

The anterior thalamic nuclei (ATN), a central component of Papez'circuit, are generally
assumed to be key constituents of the neural circuits responsible for certain categories of …

Aging is associated with specific impairments of learning and memory, some of which are
similar to those caused by hippocampal damage. Studies of the effects of aging on …

Replay of hippocampal place cell sequences has been proposed as a fundamental
mechanism of learning and memory. However, the standard interpretation of replay has …