The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

Advances in nanomaterial-based platforms to combat COVID-19: Diagnostics, preventions, therapeutics, and vaccine developments

N Mahmud, MI Anik, MK Hossain, MI Khan… - ACS Applied Bio …, 2022 - ACS Publications
The COVID-19 pandemic caused by the SARS-CoV-2, a ribonucleic acid (RNA) virus that
emerged less than two years ago but has caused nearly 6.1 million deaths to date. Recently …

2D MXenes with antiviral and immunomodulatory properties: a pilot study against SARS-CoV-2

MA Unal, F Bayrakdar, L Fusco, O Besbinar, CE Shuck… - Nano Today, 2021 - Elsevier
Two-dimensional transition metal carbides/carbonitrides known as MXenes are rapidly
growing as multimodal nanoplatforms in biomedicine. Here, taking SARS-CoV-2 as a model …

Emerging aspects of cytokine storm in COVID-19: The role of proinflammatory cytokines and therapeutic prospects

R Dharra, AK Sharma, S Datta - Cytokine, 2023 - Elsevier
COVID-19 has claimed millions of lives during the last 3 years since initial cases were
reported in Wuhan, China, in 2019. Patients with COVID-19 suffer from severe pneumonia …

Monoclonal antibodies for COVID-19 therapy and SARS-CoV-2 detection

YC Hwang, RM Lu, SC Su, PY Chiang, SH Ko… - Journal of Biomedical …, 2022 - Springer
Abstract The coronavirus disease 2019 (COVID-19) pandemic is an exceptional public
health crisis that demands the timely creation of new therapeutics and viral detection. Owing …

Immune responses in mildly versus critically ill COVID-19 patients

H Nasrollahi, AG Talepoor, Z Saleh… - Frontiers in …, 2023 - frontiersin.org
The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …

[HTML][HTML] Circulating microRNAs as emerging regulators of COVID-19

Y Liang, D Fang, X Gao, X Deng, N Chen, J Wu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the novel
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic that …

Lost microbes of COVID-19: Bifidobacterium, Faecalibacterium depletion and decreased microbiome diversity associated with SARS-CoV-2 infection severity

S Hazan, N Stollman, HS Bozkurt… - BMJ open …, 2022 - bmjopengastro.bmj.com
Objective The study objective was to compare gut microbiome diversity and composition in
SARS-CoV-2 PCR-positive patients whose symptoms ranged from asymptomatic to severe …

Current evidence on the use of anakinra in COVID-19

E Khani, M Shahrabi, H Rezaei, F Pourkarim… - International …, 2022 - Elsevier
Despite the progressing knowledge in COVID-19 management, remdesivir is the only agent
that got approval to inhibit viral replication. However, there are limited data about effective …

Bioengineered neutrophil extinguisher targets cascade immune pathways of macrophages for alleviating cytokine storm in pneumonia

A Zhou, K Chen, Y Gao, X Zhou, Z Tian, W Chen… - ACS …, 2023 - ACS Publications
Cytokine storm is a common complication of COVID-19 pneumonia and has been proven to
contribute to high mortality rates. However, current treatment approaches exhibit limited …