Neurodevelopment of the association cortices: Patterns, mechanisms, and implications for psychopathology

VJ Sydnor, B Larsen, DS Bassett, A Alexander-Bloch… - Neuron, 2021 - cell.com
The human brain undergoes a prolonged period of cortical development that spans multiple
decades. During childhood and adolescence, cortical development progresses from lower …

The Hierarchical Taxonomy of Psychopathology (HiTOP): A quantitative nosology based on consensus of evidence

R Kotov, RF Krueger, D Watson… - Annual review of …, 2021 - annualreviews.org
Traditional diagnostic systems went beyond empirical evidence on the structure of mental
health. Consequently, these diagnoses do not depict psychopathology accurately, and their …

Hierarchical models of psychopathology: Empirical support, implications, and remaining issues

BB Lahey, TM Moore, AN Kaczkurkin… - World …, 2021 - Wiley Online Library
There is an ongoing revolution in psychology and psychiatry that will likely change how we
conceptualize, study and treat psychological problems. Many theorists now support viewing …

Linking RDoC and HiTOP: A new interface for advancing psychiatric nosology and neuroscience

G Michelini, IM Palumbo, CG DeYoung… - Clinical psychology …, 2021 - Elsevier
Abstract The Research Domain Criteria (RDoC) and the Hierarchical Taxonomy of
Psychopathology (HiTOP) represent major dimensional frameworks proposing two …

Brain structural covariance networks in obsessive-compulsive disorder: a graph analysis from the ENIGMA Consortium

JY Yun, PSW Boedhoe, C Vriend, N Jahanshad, Y Abe… - Brain, 2020 - academic.oup.com
Brain structural covariance networks reflect covariation in morphology of different brain
areas and are thought to reflect common trajectories in brain development and maturation …

Altered neurocognitive functional connectivity and activation patterns underlie psychopathology in preadolescence

B Lees, LM Squeglia, LM McTeague, MK Forbes… - Biological Psychiatry …, 2021 - Elsevier
Background Neurocognitive deficits are common among youth with mental disorders, and
patterns of aberrant brain function generally cross diagnostic boundaries. This study …

Pervasively thinner neocortex as a transdiagnostic feature of general psychopathology

AL Romer, ML Elliott, AR Knodt… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: Neuroimaging research has revealed that structural brain alterations are common
across broad diagnostic families of disorders rather than specific to a single psychiatric …

Transdiagnostic dimensions of psychopathology explain individuals' unique deviations from normative neurodevelopment in brain structure

L Parkes, TM Moore, ME Calkins, PA Cook… - Translational …, 2021 - nature.com
Psychopathology is rooted in neurodevelopment. However, clinical and biological
heterogeneity, together with a focus on case-control approaches, have made it difficult to link …

Multiscale neural gradients reflect transdiagnostic effects of major psychiatric conditions on cortical morphology

B Park, V Kebets, S Larivière, MD Hettwer… - Communications …, 2022 - nature.com
It is increasingly recognized that multiple psychiatric conditions are underpinned by shared
neural pathways, affecting similar brain systems. Here, we carried out a multiscale neural …

Neurobiological, familial and genetic risk factors for dimensional psychopathology in the Adolescent Brain Cognitive Development study

M Wainberg, GR Jacobs, AN Voineskos… - Molecular …, 2022 - nature.com
Background Adolescence is a key period for brain development and the emergence of
psychopathology. The Adolescent Brain Cognitive Development (ABCD) study was created …