[HTML][HTML] Efficacy and safety of Molnupiravir in COVID-19 patients: A systematic review

KR Mali, M Eerike, GM Raj, D Bisoi… - Irish Journal of Medical …, 2023 - Springer
Background Molnupiravir is an oral antiviral drug that received Emergency Use
Authorization in three countries for the treatment of mild COVID-19. The aim of this …

[HTML][HTML] Potential herb–drug interactions between anti-COVID-19 drugs and traditional Chinese medicine

L Ye, S Fan, P Zhao, C Wu, M Liu, S Hu, P Wang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide. Effective treatments against …

[HTML][HTML] Development and validation of molnupiravir assessment in bulk powder and pharmaceutical formulation by the RP-HPLC-UV method

AM Annadi, NM El Zahar, NEDA Abdel-Sattar… - RSC …, 2022 - pubs.rsc.org
An accurate, sensitive and selective RP-HPLC-UV method has been established for the
estimation of Molnupiravir (MOL) in pure bulk powder and pharmaceutical formulation …

[HTML][HTML] Evolutionary safety of lethal mutagenesis driven by antiviral treatment

G Lobinska, Y Pilpel, MA Nowak - PLoS biology, 2023 - journals.plos.org
Nucleoside analogs are a major class of antiviral drugs. Some act by increasing the viral
mutation rate causing lethal mutagenesis of the virus. Their mutagenic capacity, however …

[HTML][HTML] The pill of recovery; Molnupiravir for treatment of COVID-19 patients; a systematic review

L Kamal, A Ramadan, S Farraj, L Bahig… - Saudi Pharmaceutical …, 2022 - Elsevier
Background Throughout the time of the global pandemic of SARS-CoV-2 virus, there has
been a compelling necessity for the development of effective antiviral agents and …

Rapid review and meta‐analysis of adverse events associated with molnupiravir in patients with COVID‐19

B Amani, S Zareei, B Amani - British Journal of Clinical …, 2022 - Wiley Online Library
Aims The aim of this study was to evaluate the safety profile of molnupiravir in COVID‐19
patients. Methods PubMed, Cochrane Library, medRxive and Google Scholar were …

[HTML][HTML] How to use COVID-19 antiviral drugs in patients with chronic kidney disease

A Kale, V Shelke, N Dagar, HJ Anders… - Frontiers in …, 2023 - frontiersin.org
Antiviral drugs such as Remdesivir (Veklury), Nirmatrelvir with Ritonavir (Paxlovid),
Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus …

[HTML][HTML] Evaluation of molnupiravir (EIDD-2801) efficacy against SARS-CoV-2 in the rhesus macaque model

DM Johnson, T Brasel, S Massey, T Garron, M Grimes… - Antiviral research, 2023 - Elsevier
Abstract Molnupiravir (EIDD-2801) is a prodrug of a ribonucleoside analogue that is
currently being used under a US FDA emergency use authorization for the treatment of mild …

[HTML][HTML] Review on molnupiravir as a promising oral drug for the treatment of COVID-19

E Zarenezhad, M Marzi - Medicinal Chemistry Research, 2022 - Springer
During the COVID-19 pandemic, various drug candidates have been developed,
molnupiravir (MK-4482 and EIDD-2801), which is a new orally anti-viral agent under …

[HTML][HTML] Real-world clinical outcomes of molnupiravir for the treatment of mild to moderate COVID-19 in adult patients during the dominance of the Omicron variant: a …

C Huang, TL Lu, L Lin - Antibiotics, 2023 - mdpi.com
Introduction: The therapeutic impact of molnupiravir in the Omicron variant phase is
unknown. The goal of the current meta-analysis was to compare the real-world clinical …