Biological Versus Chronological Aging: JACC Focus Seminar
MR Hamczyk, RM Nevado, A Barettino, V Fuster… - Journal of the American …, 2020 - jacc.org
Aging is the main risk factor for vascular disease and ensuing cardiovascular and
cerebrovascular events, the leading causes of death worldwide. In a progressively aging …
cerebrovascular events, the leading causes of death worldwide. In a progressively aging …
[HTML][HTML] Towards a consensus definition of allostatic load: a multi-cohort, multi-system, multi-biomarker individual participant data (IPD) meta-analysis
Background Allostatic load (AL) is a multi-system composite index for quantifying
physiological dysregulation caused by life course stressors. For over 30 years, an extensive …
physiological dysregulation caused by life course stressors. For over 30 years, an extensive …
Special report: the biology of inequalities in health: the lifepath consortium
Funded by the European Commission Horizon 2020 programme, the Lifepath research
consortium aimed to investigate the effects of socioeconomic inequalities on the biology of …
consortium aimed to investigate the effects of socioeconomic inequalities on the biology of …
Framework for understanding health inequalities over the life course: the embodiment dynamic and biological mechanisms of exogenous and endogenous origin
M Kelly-Irving, C Delpierre - J Epidemiol Community Health, 2021 - jech.bmj.com
Understanding how structural, social and psychosocial factors come to affect our health
resulting in health inequalities is more relevant now than ever as trends in mortality gaps …
resulting in health inequalities is more relevant now than ever as trends in mortality gaps …
Education, biological ageing, all-cause and cause-specific mortality and morbidity: UK biobank cohort study
Background Socioeconomic position as measured by education may be embodied and
affect the functioning of key physiological systems. Links between social disadvantage, its …
affect the functioning of key physiological systems. Links between social disadvantage, its …
Measuring healthy ageing: current and future tools
Human ageing is a complex, multifactorial process characterised by physiological damage,
increased risk of age-related diseases and inevitable functional deterioration. As the …
increased risk of age-related diseases and inevitable functional deterioration. As the …
Mapping intersectional inequalities in biomarkers of healthy ageing and chronic disease in older English adults
Chronic diseases and their inequalities amongst older adults are a significant public health
challenge. Prevention and treatment of chronic diseases will benefit from insight into which …
challenge. Prevention and treatment of chronic diseases will benefit from insight into which …
Understanding society at 10 years
Abstract Understanding Society: The UK Household Longitudinal Study (UKHLS) has now
been collecting a range of data from its nationally representative sample of participants for …
been collecting a range of data from its nationally representative sample of participants for …
Social mobility across the lifecourse and DNA methylation age acceleration in adults in the UK
Disadvantaged socio-economic position (SEP) is associated with greater biological age,
relative to chronological age, measured by DNA methylation (positive 'age acceleration' …
relative to chronological age, measured by DNA methylation (positive 'age acceleration' …
Metabolic profiles of socio-economic position: a multi-cohort analysis
O Robinson, AR Carter, M Ala-Korpela… - International Journal …, 2021 - academic.oup.com
Background Low socio-economic position (SEP) is a risk factor for multiple health outcomes,
but its molecular imprints in the body remain unclear. Methods We examined SEP as a …
but its molecular imprints in the body remain unclear. Methods We examined SEP as a …