Convergent evolution in SARS-CoV-2 Spike creates a variant soup that causes new COVID-19 waves

D Focosi, R Quiroga, SA McConnell, MC Johnson… - BioRxiv, 2022 - biorxiv.org
The first 2 years of the COVID-19 pandemic were mainly characterized by convergent
evolution of mutations of SARS-CoV-2 Spike protein at residues K417, L452, E484, N501 …

Acetate-encapsulated linolenic acid liposomes reduce SARS-CoV-2 and RSV infection

AR McGill, E Markoutsa, K Mayilsamy, R Green… - Viruses, 2023 - mdpi.com
Emergent Coronaviridae viruses, such as SARS-CoV-1 in 2003, MERS-CoV in 2012, and
SARS-CoV-2 (CoV-2) in 2019, have caused millions of deaths. These viruses have added to …

[HTML][HTML] Role of SARS-CoV-2 mutations in the evolution of the COVID-19 pandemic

P Colson, H Chaudet, J Delerce, P Pontarotti… - Journal of Infection, 2024 - Elsevier
Summary Objectives The SARS-CoV-2 pandemic and large-scale genomic surveillance
provided an exceptional opportunity to analyze mutations that appeared over three years in …

Antiviral activity of molnupiravir precursor NHC against SARS-CoV-2 Variants of Concern (VOCs) and its therapeutic window in a human lung cell model

T Prince, I Donovan-Banfield, H Goldswain… - bioRxiv, 2021 - biorxiv.org
Synopsis Background The UK Medicines and Regulatory Healthcare Agency (MHRA) have
recently licensed the anti-viral drug, molnupiravir, for use in patients with mild-moderate …

Molnupiravir for the treatment of COVID-19 outpatients: An updated meta-analysis

HA Cheema, SA Rab, M Butt, U Jafar, A Shahid… - Journal of Microbiology …, 2024 - Elsevier
Background The majority of available data on molnupiravir come from an unvaccinated
COVID-19 population. Therefore, we conducted this meta-analysis to integrate evidence …

[HTML][HTML] Convalescent plasma for COVID-19 in oncohematological patients: a call for revision of the European Conference on Infections in Leukemia-9 (ECIL-9) …

D Focosi, M Franchini, JW Senefeld… - Journal of Clinical …, 2023 - ncbi.nlm.nih.gov
The recommendations for the management of COVID-19 in patients with hematological
malignancies or hematopoietic cell transplantation, from the 2021 European Conference on …

Shedding Light on Dark Chemical Matter: The Discovery of a SARS-CoV-2 Mpro Main Protease Inhibitor through Intensive Virtual Screening and In Vitro Evaluation

MN Peralta-Moreno, Y Mena, D Ortega-Alarcon… - International Journal of …, 2024 - mdpi.com
The development of specific antiviral therapies targeting SARS-CoV-2 remains fundamental
because of the continued high incidence of COVID-19 and limited accessibility to antivirals …

The Role of Convalescent Plasma in COVID-19: A Conclusive Post-Pandemic Review

M Franchini, D Focosi - Life, 2023 - mdpi.com
COVID-19 convalescent plasma (CCP) has represented the frontline response to the COVID-
19 pandemic, largely because of encouraging historical evidences in previous pandemics …

The impact of vaccination frequency on COVID-19 public health outcomes: A model-based analysis

M Stoddard, L Yuan, S Sarkar, D van Egeren… - medRxiv, 2023 - medrxiv.org
While the rapid deployment of SARS-CoV-2 vaccines had a significant impact on the
ongoing COVID-19 pandemic, rapid viral immune evasion and waning neutralizing antibody …

Effect of Nucleic Acid Analog Administration on Fluctuations in the Albumin-to-Globulin Ratio in Cats with Feline Infectious Peritonitis

M Katayama, Y Uemura, D Katori - Animals, 2024 - mdpi.com
Simple Summary A total of 122 and 56 cats with feline infectious peritonitis achieved
remission after the administration of Mutian and molnupiravir (nucleic acid analogs with …