Microbial pathogens have threatened the world due to their pathogenicity and ability to
spread in communities. The conventional laboratory‐based diagnostics of microbes such as …

Inflammation plays a critical role in the response to and survival from injuries and/or
infections. It occurs in two phases: initiation and resolution; however, when these events do …

Macrophages are cells of the innate immune system and represent an important component
of the first-line defense against pathogens and tumor cells. Here, their diverse functions in …

BAM15 (a mitochondrial uncoupling agent) was tested on cecal ligation and puncture (CLP)
sepsis mice with in vitro experiments. BAM15 attenuated sepsis as indicated by survival …

Cancer is the leading cause of death worldwide. Cancer immunotherapy involves
reinvigorating the patient's own immune system to fight against cancer. While novel …

Severe bacterial pneumonia leads to acute respiratory distress syndrome (ARDS), with a
high incidence rate and mortality. It is well-known that continuous and dysregulated …

Sepsis associated encephalopathy, occurs in 70% of severe septic cases, following which
survivors exhibit long-term cognitive impairment or global loss of cognitive function …

Background Understanding the molecular pathogenesis of inflammatory bowel disease
(IBD) has led to the discovery of new therapeutic targets that are more specific and effective …

For more than 40 years, the epipodophyllotoxin drug etoposide is prescribed to treat cancer.
This semi-synthetic compound remains extensively used to treat advanced small-cell lung …

The term “cytokine storm” describes an acute pathophysiologic state of the immune system
characterized by a burst of cytokine release, systemic inflammatory response, and multiple …